Document Detail

Immunocompetent cells among mouse thymocytes: a minor population.
MedLine Citation:
PMID:  4396965     Owner:  NLM     Status:  MEDLINE    
Suspensions prepared from thymuses of TL(+) mice contain a majority of TL(+) cells and a minority of TL(-) cells. The graft versus host reactivity of the TL(-) population is much greater than that of the whole population, as judged by the numbers of cells required to give splenic enlargements in Simonsen's assay. It is proposed that the TL(-) thymocyte represents a stage in the differentiation of TL(+) thymocytes into immunocompetent lymphocytes.
E Leckband; E A Boyse
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  172     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1971 Jun 
Date Detail:
Created Date:  1971-07-06     Completed Date:  1971-07-06     Revised Date:  2011-12-13    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1258-60     Citation Subset:  IM    
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MeSH Terms
Graft vs Host Reaction*
Immune Sera
Spleen / immunology
Thymus Gland / cytology,  immunology*
Reg. No./Substance:
0/Antigens; 0/Immune Sera

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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