Document Detail

Immunocompetence and its costs during development: an experimental study in blue tit nestlings.
MedLine Citation:
PMID:  15101435     Owner:  NLM     Status:  MEDLINE    
The allocation into T-cell-mediated immunocompetence was experimentally increased in 68 out of 139 nestlings by supplementary feeding methionine to half of the nestlings in 15 blue tit nests. Methionine-supplemented nestlings had an increased T-cell-mediated immunocompetence, but a reduced growth compared with control siblings. Nestlings that had low initial weights and nestlings that were supplemented with methionine had an increased mortality risk. The investment that nestling blue tits make in immunocompetence appears to be tightly controlled by survival costs paid through a trade-off between immunocompetence and growth.
Jon E Brommer
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Proceedings. Biological sciences / The Royal Society     Volume:  271 Suppl 3     ISSN:  0962-8452     ISO Abbreviation:  Proc. Biol. Sci.     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-04-22     Completed Date:  2004-05-21     Revised Date:  2010-09-20    
Medline Journal Info:
Nlm Unique ID:  101245157     Medline TA:  Proc Biol Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  S110-3     Citation Subset:  IM    
Bird Ecology Unit, Department of Ecology and Systematics, PO Box 65 (Viikinkaari 1), University of Helsinki, FIN 00014 Helsinki, Finland.
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MeSH Terms
Body Weight
Immunocompetence / drug effects*
Methionine / immunology,  pharmacology
Songbirds / growth & development*,  immunology*
T-Lymphocytes / immunology*
Reg. No./Substance:
0/Phytohemagglutinins; 63-68-3/Methionine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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