Document Detail

Immunochemical studies of infectious mononucleosis. VII. Isolation and partial characterization of a glycopeptide from bovine erythrocytes.
MedLine Citation:
PMID:  898834     Owner:  NLM     Status:  MEDLINE    
The major sialoglycopeptide released from bovine erythrocytes by papain has been purified and characterized. The glycopeptide contains 82% by weight carbohydrate in molar ratios of galactose - 5.5:N-acetylglucosamine - 3.6:sialic acid - 2.6:N-acetylgalactosamine - 1.0. The carbohydrate and amino acid composition is quite different from the glycoprotein extracted from bovine erythrocyte stroma with hot 75% ethanol. The glycopeptide is devoid of reactivity with Paul-Bunnell heterophile antibody of infectious mononucleosis - an activity expressed to high degree on the bovine erythrocyte and associated with glycoprotein. The glycopeptide does react, however, with another antibody found in infectious mononucleosis as well as most normal human sera tested.
M A Fletcher; T M Lo; W R Graves
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Vox sanguinis     Volume:  33     ISSN:  0042-9007     ISO Abbreviation:  Vox Sang.     Publication Date:  1977 Sep 
Date Detail:
Created Date:  1977-10-14     Completed Date:  1977-10-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0413606     Medline TA:  Vox Sang     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  150-63     Citation Subset:  IM    
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MeSH Terms
Chromatography, Gel
Electrophoresis, Polyacrylamide Gel
Erythrocytes / immunology*
Hemagglutination Inhibition Tests
Infectious Mononucleosis / immunology*
Sialoglycoproteins / isolation & purification*,  pharmacology
Reg. No./Substance:

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