| Immunochemical pattern of aspartate aminotransferase isozumes in servral rodents and in Ehrlich ascites cells (38549). | |
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MedLine Citation:
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PMID: 47635 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Antisera against rat liver aspartate aminotransferase (EC 2.6.1.1) isozymes were used to study the activity and immunologic pattern of these isozymes in the livers of the rat, mouse, hamster, gerbil and in Ehrlich ascites cells. A double immunodiffusion precipitin test and immunoelectrophoresis showed that, except for the gerbil, there was a pattern of identity of AAT isozymes in the presence of either the antianionic or the anticationic antisera. Although gerbil AAT isozymes are immunochemically different from those of the other rodents studied, they were inactivated by the respective antiserum in a manner similar to that observed with the other species. This may suggest that antigenic determinants at the catalytic site of each of the liver aspartate aminotransferase isozymes are least likely to change throughout the evolutionary process. |
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Authors:
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L Kopelovich |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) Volume: 148 ISSN: 0037-9727 ISO Abbreviation: Proc. Soc. Exp. Biol. Med. Publication Date: 1975 Feb |
Date Detail:
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Created Date: 1975-06-21 Completed Date: 1975-06-21 Revised Date: 2007-11-02 |
Medline Journal Info:
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Nlm Unique ID: 7505892 Medline TA: Proc Soc Exp Biol Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 410-3 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aspartate Aminotransferases / immunology, metabolism* Carcinoma, Ehrlich Tumor / enzymology* Cricetinae Cross Reactions Epitopes Gerbillinae Immune Sera Immunodiffusion Immunoelectrophoresis Isoenzymes / metabolism* Liver / enzymology* Male Mice Mice, Inbred C3H Rats Rats, Inbred BUF Rodentia / metabolism* Species Specificity |
| Chemical | |
Reg. No./Substance:
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0/Epitopes; 0/Immune Sera; 0/Isoenzymes; EC 2.6.1.1/Aspartate Aminotransferases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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