| Immunoanalysis of three litters born to a Doberman bitch infected with Neospora caninum. | |
| | |
MedLine Citation:
|
PMID: 17096148 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Neospora caninum is a tissue cyst-forming coccidium that may cause neuromuscular disorders in dogs. Infected bitches can transmit the parasite to their pups in utero. Vertical transmission may occur after primary infection during pregnancy and in subsequent pregnancies. The reason why only a few pups develop clinical neosporosis is unknown. We obtained sera from a Doberman bitch and its offspring delivered in three litters. The bitch had a titer of 1:640 in an indirect fluorescent antibody test (IFAT). At least three pups of litter A, one pup of litter B, and two pups of litter C were also seropositive for N. caninum. However, clinical neosporosis developed only in one pup of litter C, which had the highest IFAT titer (1:5,120) of all dogs examined. Western blots carried out after one-dimensional and two-dimensional separation of N. caninum tachyzoites revealed that the largest number of antigens was recognized by sera derived from the bitch. The lowest number of antigens was recognized by serum from the pup with clinical neosporosis. However, this pup uniquely recognized a major antigen with a molecular weight of about 17,000. The information collected in this study adds to our knowledge on why some pups develop clinical neosporosis and others do not. |
| | |
Authors:
|
A R Heckeroth; A M Tenter |
Related Documents
:
|
1768788 - Effect of extra-genital schistosoma mansoni and echinostoma caproni infections on serum... 22399208 - Yoga during pregnancy: a review. 7198968 - Coitus and chorioamnionitis: a prospective study. 16721858 - Alanine transaminase levels in the year before pregnancy predict the risk of hepatitis ... 15715608 - Impact of medically assisted fertility on preterm birth. 522768 - Clomiphene-induced pregnancy in a patient with diabetes insipidus and hypothyroidism. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-11-10 |
Journal Detail:
|
Title: Parasitology research Volume: 100 ISSN: 0932-0113 ISO Abbreviation: Parasitol. Res. Publication Date: 2007 Mar |
Date Detail:
|
Created Date: 2007-01-25 Completed Date: 2007-09-28 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 8703571 Medline TA: Parasitol Res Country: Germany |
Other Details:
|
Languages: eng Pagination: 837-46 Citation Subset: IM |
Affiliation:
|
Intervet Innovation GmbH, Zur Propstei, 55270, Schwabenheim, Germany. anja.heckeroth@intervet.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Antibodies, Protozoan Carrier State Cercopithecus aethiops Coccidiosis / immunology, transmission, veterinary* Dog Diseases / immunology, transmission* Dogs Female Infectious Disease Transmission, Vertical Male Neospora / isolation & purification* Pregnancy Vero Cells |
| Chemical | |
Reg. No./Substance:
|
0/Antibodies, Protozoan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Co-invasion of a Red Sea fish and its ectoparasitic monogenean, Polylabris cf. mamaevi into the Medi...
Next Document: No variation in the prevalence of point mutations in the Pfcrt and Pfmdr1 genes in isolates from Gab...