Document Detail


Immunization registry-based recall for a new vaccine.
MedLine Citation:
PMID:  12437389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Immunization recall for specific vaccines may be necessary to "catch up" children with newly available vaccines or recall children after vaccine shortages. The extent to which immunization registry-based recall can increase immunization rates for a new vaccine has not been prospectively studied. OBJECTIVE: To assess the efficacy of letter/telephone recall for immunization with pneumococcal conjugate vaccine (PCV7) in an economically disadvantaged urban population. DESIGN/METHODS: Randomized controlled trial at an inner-city teaching hospital. Using an immunization registry, we randomly assigned children aged 6 weeks to 22 months unimmunized for PCV7 to an intervention group (n = 610) or a control group (n = 624). The intervention consisted of letter and telephone recall for PCV7 vaccination. Two months after intervention, receipt of 1 or more doses of PCV7 was assessed. Intention-to-treat analysis was used. RESULTS: We were unable to successfully contact 42.3% of the intervention subjects by mail and telephone. In the intervention group, 23.0% (140 children) received PCV7 within 2 months compared with 20.2% (126 children) in the control group (P = NS). No intervention effect was evident when children were stratified by age. A large proportion of the study population had Medicaid insurance (51.2%) or were uninsured (28.5%), but response to PCV7 recall did not vary by insurance status. CONCLUSIONS: Letter and telephone recall for PCV7 vaccine did not significantly increase the rate of PCV7 immunization in an inner-city teaching hospital serving a disadvantaged population. The effectiveness of recall appears to have been limited by the inability to reach many subjects by mail and telephone.
Authors:
Matthew F Daley; John F Steiner; Robert M Brayden; Stanley Xu; Stephanie Morrison; Allison Kempe
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Ambulatory pediatrics : the official journal of the Ambulatory Pediatric Association     Volume:  2     ISSN:  1530-1567     ISO Abbreviation:  Ambul Pediatr     Publication Date:    2002 Nov-Dec
Date Detail:
Created Date:  2002-11-19     Completed Date:  2002-12-27     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  101089367     Medline TA:  Ambul Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  438-43     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Colorado Health Sciences Center, The Children's Hospital, Denver 80218, USA. daley.matthew@tchden.org
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Colorado
Female
Humans
Immunization Programs*
Infant
Male
Pneumococcal Vaccines
Postal Service
Poverty Areas
Prospective Studies
Registries*
Reminder Systems*
Statistics, Nonparametric
Telephone
Grant Support
ID/Acronym/Agency:
2-D08-PE-50019/PE/BHP HRSA HHS; U66/CCU812972-05/CC/CDC HHS
Chemical
Reg. No./Substance:
0/Pneumococcal Vaccines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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