Document Detail

Immunization of preterm and low birth weight infants. American Academy of Pediatrics Committee on Infectious Diseases.
MedLine Citation:
PMID:  12837889     Owner:  NLM     Status:  MEDLINE    
Preterm (PT) infants are at increased risk of experiencing complications of vaccine-preventable diseases but are less likely to receive immunizations on time. Medically stable PT and low birth weight (LBW) infants should receive full doses of diphtheria, tetanus, acellular pertussis, Haemophilus influenzae type b, hepatitis B, poliovirus, and pneumococcal conjugate vaccines at a chronologic age consistent with the schedule recommended for full-term infants. Infants with birth weight less than 2000 g may require modification of the timing of hepatitis B immunoprophylaxis depending on maternal hepatitis B surface antigen status. All PT and LBW infants benefit from receiving influenza vaccine beginning at 6 months of age before the beginning of and during the influenza season. All vaccines routinely recommended during infancy are safe for use in PT and LBW infants. The occurrence of mild vaccine-attributable adverse events are similar in both full-term and PT vaccine recipients. Although the immunogenicity of some childhood vaccines may be decreased in the smallest PT infants, antibody concentrations achieved usually are protective.
Thomas N Saari;
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Publication Detail:
Type:  Guideline; Journal Article; Practice Guideline    
Journal Detail:
Title:  Pediatrics     Volume:  112     ISSN:  1098-4275     ISO Abbreviation:  Pediatrics     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-07-02     Completed Date:  2003-12-18     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  193-8     Citation Subset:  AIM; IM    
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MeSH Terms
Bacterial Capsules
Diphtheria-Tetanus-Pertussis Vaccine / administration & dosage
Haemophilus Vaccines / administration & dosage
Hepatitis B
Hepatitis B Vaccines / administration & dosage
Immunization Schedule
Immunoglobulins / administration & dosage
Infant, Low Birth Weight*
Infant, Newborn
Infant, Premature*
Influenza Vaccines / administration & dosage
Pneumococcal Vaccines / administration & dosage
Poliovirus Vaccine, Oral / administration & dosage
Polysaccharides, Bacterial / administration & dosage
Pregnancy Complications, Infectious
Vaccination* / adverse effects
Vaccines / administration & dosage*,  adverse effects
Vaccines, Conjugate / administration & dosage
Reg. No./Substance:
0/Bacterial Capsules; 0/Diphtheria-Tetanus-Pertussis Vaccine; 0/Haemophilus Vaccines; 0/Haemophilus influenzae type b polysaccharide vaccine; 0/Hepatitis B Vaccines; 0/Immunoglobulins; 0/Influenza Vaccines; 0/Pneumococcal Vaccines; 0/Poliovirus Vaccine, Oral; 0/Polysaccharides, Bacterial; 0/Vaccines; 0/Vaccines, Conjugate; 0/hepatitis B hyperimmune globulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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