| Immunization levels among premature and low-birth-weight infants and risk factors for delayed up-to-date immunization status. Centers for Disease Control and Prevention Vaccine Safety Datalink Group. | |
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MedLine Citation:
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PMID: 10450716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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CONTEXT: Studies have noted that health care professionals may not conform to proper immunization schedules for premature and low-birth-weight infants in the United States. Little is known about the success of current efforts to immunize these high-risk infants. OBJECTIVE: To describe current immunization practices for premature and low-birth-weight infants and ascertain risk factors for poor immunization status, using large population-based data sources. DESIGN AND SETTING: Cohort and case-control analyses of immunization data tracked from March 1991 through March 1997 for 3 large health maintenance organizations (HMOs) participating in the Centers for Disease Control and Prevention's Vaccine Safety Datalink project. PARTICIPANTS: A total of 11580 low-birth-weight and premature infants were enrolled from birth to age 2 months; 6832 of these were continuously enrolled from birth to age 24 months. At age 2 months, there were 173373 full-term, normal-birth-weight infants enrolled as controls; at age 24 months, there were 103 324. MAIN OUTCOME MEASURES: Age-specific immunization status by prematurity and birth weight (<1500 g, 1500-2500 g, born at <38 weeks' gestation with birth weight of >2500 g, or full-term with normal birth weight) and patient characteristics associated with up-to-date status. RESULTS: At each age, infants weighing less than 1500 g at birth had lower up-to-date immunization levels than other infants. At age 6 months, 52% to 65% of infants weighing less than 1500 g were up-to-date at each of the 3 HMOs compared with 69% to 73% of those weighing 1500 to 2500 g, 66% to 80% of premature infants weighing more than 2500 g, and 65% to 76% of full-term, normal-birth-weight infants. By age 24 months, 78% to 86% of infants weighing less than 1500 g were up-to-date, significantly less than heavier infants, who had levels of 84% to 89%. Well-child preventive care strongly predicted immunization status, while concomitant pulmonary disease did not. CONCLUSIONS: Our data suggest that infants born prematurely are vaccinated at levels approaching that of the general population, but levels of vaccination for very low-birth-weight infants lag slightly behind. |
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Authors:
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R L Davis; D Rubanowice; H R Shinefield; N Lewis; D Gu; S B Black; F DeStefano; P Gargiullo; J P Mullooly; R S Thompson; R T Chen |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: JAMA : the journal of the American Medical Association Volume: 282 ISSN: 0098-7484 ISO Abbreviation: JAMA Publication Date: 1999 Aug |
Date Detail:
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Created Date: 1999-08-19 Completed Date: 1999-08-19 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7501160 Medline TA: JAMA Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 547-53 Citation Subset: AIM; IM |
Affiliation:
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Immunization Studies Program, Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, Wash, USA. rdavis@u.washington.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Health Maintenance Organizations
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standards,
statistics & numerical data Humans Immunization Schedule Infant Infant, Low Birth Weight* / immunology Infant, Newborn Infant, Premature* / immunology Infant, Premature, Diseases / immunology Logistic Models Lung Diseases / immunology Population Surveillance Risk Factors United States Vaccination / standards, utilization* |
| Grant Support | |
ID/Acronym/Agency:
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200-95-0947//PHS HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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