Document Detail


Immune system: maturation of myeloid cells.
MedLine Citation:
PMID:  19495705     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Human and animal cell lines are important laboratory tools that can be used for studying a variety of cell functions. Some cell lines are blocked at a certain step of maturation and can be used in order to study the mechanisms involved in cell maturation. Because such cell lines can be differentiated toward a more mature-like phenotype after the addition of agents, they can replace primary cells in large screening experiments preventing daily isolation. The human promyelocytic HL-60 leukemia cell line is an attractive model for studying the events which occur in myeloid cells. Interestingly, these cells can be differentiated toward monocytes, macrophages, or granulocytes as described in the present chapter.
Authors:
Jamila Ennaciri; Denis Girard
Related Documents :
16931585 - Defining ploidy-specific thresholds in array comparative genomic hybridization to impro...
9723165 - Uv-induced melanoma cell lines and their potential for proteome analysis: a review.
6979385 - Antitumor activity of d-mannosamine in vitro: different sensitivities among human leuke...
9648105 - Invertebrate cell culture considerations: insects, ticks, shellfish, and worms.
9242365 - Actinomycin d treatment leads to differentiation and inhibits proliferation in rhabdomy...
22297735 - Antiviral function and efficacy of polyvalent immunoglobulin products against cmv isola...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  550     ISSN:  1064-3745     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2009  
Date Detail:
Created Date:  2009-06-04     Completed Date:  2009-09-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  195-203     Citation Subset:  IM    
Affiliation:
Laboratoire de recherche en inflammation et physiologie des granulocytes, Institut National de la Recherche Scientifique (INRS) - Institut Armand Frappier, Université du Québec, Laval, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Bone Marrow Cells / cytology,  immunology*
Cell Differentiation
Eosinophils / cytology
Flow Cytometry
HL-60 Cells
Humans
Macrophages / cytology
Neutrophils / cytology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Genetic Dissection of Caenorhabditis elegans Embryogenesis Using RNA Interference and Flow Cytometry...
Next Document:  Functional development of human fetal gastrointestinal tract.