| Immune responses during pregnancy and the development of allergic disease. | |
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MedLine Citation:
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PMID: 9455773 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is now established that allergen exposure in the first few months of life is important in the development of specific allergic sensitisation (1, 2). Furthermore, the immune response of infants born to families with a strong history of allergic disease is relatively immature at birth in comparison to infants with no family history of allergies, with reduced production of Interferon-gamma (IFN-gamma) (3-5) and lower levels of T cell activation and memory (6). It therefore seems logical that the interaction of these two factors must be important in the ontogeny of allergic disease. |
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Authors:
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J A Warner; C A Jones; A C Jones; E A Miles; T Francis; J O Warner |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology Volume: 8 ISSN: 0905-6157 ISO Abbreviation: Pediatr Allergy Immunol Publication Date: 1997 |
Date Detail:
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Created Date: 1998-03-13 Completed Date: 1998-03-13 Revised Date: 2008-05-28 |
Medline Journal Info:
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Nlm Unique ID: 9106718 Medline TA: Pediatr Allergy Immunol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 5-10 Citation Subset: IM |
Affiliation:
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University Child Health, University of Southampton, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Allergens
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immunology* Animals Embryonic and Fetal Development / immunology* Female Humans Hypersensitivity / etiology*, immunology Immune System / embryology* Pregnancy / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Allergens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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