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Immune deficiency, thrombocytopenia and osteomyelitis in pediatric patients.
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MedLine Citation:
PMID:  751324     Owner:  NLM     Status:  MEDLINE    
Surgical decompression of osteomyelitis in pediatric patients should be an essential part of therapy in most cases. The initial deferral of prompt decompression in two patients because of underlying chronic, hemorrhagic (thrombocytopenic) disorders-one with Wiskott-Aldrich syndrome and one with Gaucher's disease-resulted in more serious and prolonged courses of the infectious processes. The complications might have been ameliorated by earlier drainage in each case. Based upon the experience gained from these two patients, we recommend early drainage, with appropriate treatment of the hemorrhagic disorder, to prevent more widespread dissemination or prolongation of osseous infection in similarly affected children.
C R Clark; K E Lee; J A Ogden; L S McIntosh
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Yale journal of biology and medicine     Volume:  51     ISSN:  0044-0086     ISO Abbreviation:  Yale J Biol Med     Publication Date:    1978 Jul-Aug
Date Detail:
Created Date:  1979-07-25     Completed Date:  1979-07-25     Revised Date:  2012-05-30    
Medline Journal Info:
Nlm Unique ID:  0417414     Medline TA:  Yale J Biol Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  435-40     Citation Subset:  IM    
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MeSH Terms
Blood Transfusion
Child, Preschool
Gaucher Disease / complications
Immunologic Deficiency Syndromes / complications*
Osteomyelitis / complications,  surgery*
Preoperative Care
Thrombocytopenia / complications*
Wiskott-Aldrich Syndrome / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Yale J Biol Med
ISSN: 0044-0086
ISSN: 1551-4056
Article Information
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Print publication date: Season: Jul?Aug Year: 1978
Volume: 51 Issue: 4
First Page: 435 Last Page: 440
ID: 2595619
PubMed Id: 751324
PubMed Id: 751324

Immune Deficiency, Thrombocytopenia and Osteomyelitis in Pediatric Patients
Charles R. Clark
Kendrick E. Lee
John A. Ogden
L. Sue McIntosh

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