Document Detail

Immediate postoperative intraocular pressure measurements after trabeculectomy with releasable sutures.
MedLine Citation:
PMID:  17073901     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To assess the practicality of same-day intraocular pressure (IOP) review following trabeculectomy with releasable sutures. It is a prospective observational case series study. METHODS: 40 eyes of patients undergoing inpatient trabeculectomy for glaucoma optic neuropathy. IOP measurement at 2, 4, 8, 12 and 24 h following trabeculectomy with releasable sutures. Slit-lamp microscopy documenting surgical complications. RESULTS: Three patients required intervention within the first 24 h and four patients at 24 h because of raised IOP. Investigating pressure outcomes of low (<8 mmHg) and high (>21 mmHg) the sensitivity and specificity of IOP assessments at 2, 4, 8 and 12 h were compared with a 'gold standard' of IOP at 24 h postoperatively. False negative results persist at time periods for low IOP and are absent for high IOP only at 8 h postoperatively. There is a marked change in IOP over the first 24-h period in some patients, both from high to low and from low to high levels. CONCLUSIONS: Same-day review of trabeculectomy is not a practical proposition as a policy for a unit with present operative techniques. Indeed the finding of transient high pressures during the first 24 h in some cases suggests that in those patients for whom there is concern (mainly those with severe disc cupping at the time of surgery) at least one IOP check during the first 24 h postoperatively may be warranted in addition to the 24-h postoperative check.
Jodhbir S Mehta; Vincenzo Maurino; Hemankumar Patel; James Kirwin; Ian E Murdoch
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical & experimental ophthalmology     Volume:  34     ISSN:  1442-6404     ISO Abbreviation:  Clin. Experiment. Ophthalmol.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-31     Completed Date:  2007-01-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100896531     Medline TA:  Clin Experiment Ophthalmol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  778-82     Citation Subset:  IM    
Glaucoma Service, Moorfields Eye Hospital, London, UK.
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MeSH Terms
Aged, 80 and over
Combined Modality Therapy
False Negative Reactions
Fluorouracil / administration & dosage
Glaucoma / physiopathology,  surgery*
Intraocular Pressure / physiology*
Middle Aged
Mitomycin / administration & dosage
Optic Nerve Diseases / physiopathology,  surgery*
Postoperative Period
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Suture Techniques*
Tonometry, Ocular
Trabeculectomy / methods*
Reg. No./Substance:
50-07-7/Mitomycin; 51-21-8/Fluorouracil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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