Document Detail


Immediate coronary angiography in survivors of out-of-hospital cardiac arrest.
MedLine Citation:
PMID:  9171064     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The incidence of acute coronary-artery occlusion among patients with sudden cardiac arrest outside of the hospital is unknown, and the role of reperfusion therapy has not been determined. We therefore performed immediate coronary angiography and angioplasty when indicated in survivors of out-of-hospital cardiac arrest. METHODS: Between September 1994 and August 1996, coronary angiography was performed in 84 consecutive patients between the ages of 30 and 75 years who had no obvious noncardiac cause of cardiac arrest. RESULTS: Sixty of the 84 patients had clinically significant coronary disease on angiography, 40 of whom had coronary-artery occlusion (48 percent). Angioplasty was attempted in 37 patients and was technically successful in 28. Clinical and electrocardiographic findings, such as the occurrence of chest pain and the presence of ST-segment elevation, were poor predictors of acute coronary-artery occlusion. The in-hospital survival rate was 38 percent. Multivariate logistic-regression analysis revealed that successful angioplasty was an independent predictor of survival (odds ratio, 5.2; 95 percent confidence interval, 1.1 to 24.5; P=0.04). CONCLUSIONS: Acute coronary-artery occlusion is frequent in survivors of out-of-hospital cardiac arrest and is predicted poorly by clinical and electrocardiographic findings. Accurate diagnosis by immediate coronary angiography can be followed in suitable candidates by coronary angioplasty, which seems to improve survival.
Authors:
C M Spaulding; L M Joly; A Rosenberg; M Monchi; S N Weber; J F Dhainaut; P Carli
Related Documents :
1828144 - Monitoring functional patency of percutaneous transluminal angioplasty.
9293824 - Saphenous vein versus polytetrafluoroethylene carotid patch angioplasty.
8517424 - Rehospitalizations after coronary revascularization among medicare beneficiaries.
9120174 - Randomized comparison of primary coronary angioplasty with thrombolytic therapy in low ...
8915994 - Electrocardiographic observation on spontaneously occurring arrhythmias in chickens.
16567294 - Electrophysiological consequence of skeletal myoblast transplantation in normal and inf...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New England journal of medicine     Volume:  336     ISSN:  0028-4793     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-06-05     Completed Date:  1997-06-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1629-33     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, Cochin Hospital, René Descartes University, Paris, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angioplasty, Transluminal, Percutaneous Coronary
Coronary Angiography*
Coronary Disease / complications,  diagnosis*,  mortality,  therapy
Electrocardiography
Female
Heart Arrest / etiology,  radiography*
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Prospective Studies
Survival Analysis
Survivors
Comments/Corrections
Comment In:
N Engl J Med. 1997 Oct 30;337(18):1321-2   [PMID:  9380089 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PA...
Next Document:  Epidural corticosteroid injections for sciatica due to herniated nucleus pulposus.