| Immediate complications after medical compared with surgical termination of pregnancy. | |
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MedLine Citation:
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PMID: 19888037 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To estimate the immediate adverse events and safety of medical compared with surgical abortion using high-quality registry data. METHODS: All women in Finland undergoing induced abortion from 2000-2006 with a gestational duration of 63 days or less (n=42,619) were followed up until 42 days postabortion using national health registries. The incidence and risk factors of adverse events after medical (n=22,368) and surgical (n=20,251) abortion were compared. Univariable and multivariable association models were used to analyze the risk of the three main complications (hemorrhage, infection, and incomplete abortion) and surgical (re)evacuation. RESULTS: The overall incidence of adverse events was fourfold higher in the medical compared with surgical abortion cohort (20.0% compared with 5.6%, P<.001). Hemorrhage (15.6% compared with 2.1%, P<.001) and incomplete abortion (6.7% compared with 1.6%, P<.001) were more common after medical abortion. The rate of surgical (re)evacuation was 5.9% after medical abortion and 1.8% after surgical abortion (P<.001). Although rare, injuries requiring operative treatment or operative complications occurred more often with surgical termination of pregnancy (0.6% compared with 0.03%, P<.001). No differences were noted in the incidence of infections (1.7% compared with 1.7%, P=.85), thromboembolic disease, psychiatric morbidity, or death. CONCLUSION: Both methods of abortion are generally safe, but medical termination is associated with a higher incidence of adverse events. These observations are relevant when counseling women seeking early abortion. LEVEL OF EVIDENCE: II. |
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Authors:
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Maarit Niinim?ki; Anneli Pouta; Aini Bloigu; Mika Gissler; Elina Hemminki; Satu Suhonen; Oskari Heikinheimo |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 114 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-11-05 Completed Date: 2009-12-02 Revised Date: 2010-03-04 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 795-804 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents
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adverse effects* Abortion, Induced / adverse effects* Adult Cohort Studies Female Gestational Age Humans Odds Ratio Pregnancy Reoperation Uterine Hemorrhage / etiology* Vacuum Curettage / adverse effects* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents |
| Comments/Corrections | |
Comment In:
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Obstet Gynecol. 2010 Mar;115(3):660; author reply 660-1
[PMID:
20177301
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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