Document Detail

Immediate anatomic results after the endovascular treatment of ruptured intracranial aneurysms: analysis in the CLARITY series.
MedLine Citation:
PMID:  20075090     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: The efficacy of the endovascular treatment in providing stable occlusion of intracranial aneurysms is still controversial and should be precisely analyzed. A first step is to carefully study immediate anatomical results. CLARITY (Clinical and Anatomical Results in the Treatment of Ruptured Intracranial Aneurysms) is a prospective multicenter consecutive series including patients treated by coiling for ruptured aneurysms. Immediate anatomic results are presented. MATERIALS AND METHODS: Postoperative anatomic results were evaluated by DSA by the treating physician and anonymously and independently by 2 experienced neuroradiologists by using the 3-point Montreal Scale. Patients were divided into 2 groups: patients treated with GDC and those treated with Matrix detachable coils. RESULTS: A total of 773 patients (461 women, 312 men; 19-80 years of age; mean, 51.2 +/- 13.2 years) with 773 ruptured aneurysms were included in the study. The rate of occlusion as determined by the treating physician was designated complete for 586 aneurysms (75.8%), neck remnant for 145 aneurysms (18.8%), and aneurysm remnant for 42 aneurysms (5.4%). The same evaluation as reported by the 2 independent reviewers was complete occlusion for 366 aneurysms (47.4%), neck remnant for 324 aneurysms (41.9%), and aneurysm remnant for 83 aneurysms (10.7%). Postoperative anatomic results were significantly linked to age but not to the technique of endovascular treatment or aneurysm characteristics (location, size, dome-to neck ratio). Results were not significantly different between the GDC and Matrix group. CONCLUSIONS: Endovascular treatment of ruptured intracranial aneurysms resulted in a high rate of satisfactory occlusion (complete occlusion and neck remnant in 89.3%). Patient age was the only factor associated with the rate of occlusion. The rate of aneurysm occlusion differed insignificantly between GDC and Matrix coils.
L Pierot; C Cognard; F Ricolfi; R Anxionnat;
Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't     Date:  2010-01-14
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  31     ISSN:  1936-959X     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-17     Completed Date:  2010-09-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  907-11     Citation Subset:  IM    
Department of Neuroradiology, Maison Blanche Hospital, CHU Reims, Reims, France.
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MeSH Terms
Aged, 80 and over
Aneurysm, Ruptured / radiography*,  surgery*
Embolization, Therapeutic / instrumentation*
Intracranial Aneurysm / radiography*,  surgery*
Middle Aged
Treatment Outcome
Young Adult
Anne Pasco / ; Jean-François Bonneville / ; Xavier Barreau / ; Jérôme Berge / ; Patrick Courthéoux / ; Suzana Saleme / ; Emmanuel Chabert / ; Jean Gabrillargues / ; Xavier Leclerc / ; Jean-Pierre Pruvo / ; Christian Taschner / ; Olivier Lévrier / ; Alain Bonafé / ; Hubert Desal / ; Axel de Kersaint-Gilly / ; Alessandra Biondi / ; Fabrice Bonneville / ; Betty Jean / ; Nader Sourour / ; Jacques Moret / ; Charbel Mounayer / ; Michel Piotin / ; Laurent Spelle / ; Raphaël Blanc / ; Sylvie Gordon-Hardy / ; Jean-François Meder / ; Denis Trystram / ; Jacques Drouineau / ; Sophie Gallas / ; Laurent Pierot / ; Fabrice-Guy Barral / ; Luis Manera / ; Rémy Beaujeux / ; Fazel Boujan / ; Charles Arteaga / ; Christophe Cognard / ; Anne-Christine Januel / ; Philippe Tal / ; Denis Herbreteau / ; Richard Bibi / ; Yves Chau / ; Jacques Sedat /

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