| Immediate anatomic results after the endovascular treatment of ruptured intracranial aneurysms: analysis in the CLARITY series. | |
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MedLine Citation:
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PMID: 20075090 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: The efficacy of the endovascular treatment in providing stable occlusion of intracranial aneurysms is still controversial and should be precisely analyzed. A first step is to carefully study immediate anatomical results. CLARITY (Clinical and Anatomical Results in the Treatment of Ruptured Intracranial Aneurysms) is a prospective multicenter consecutive series including patients treated by coiling for ruptured aneurysms. Immediate anatomic results are presented. MATERIALS AND METHODS: Postoperative anatomic results were evaluated by DSA by the treating physician and anonymously and independently by 2 experienced neuroradiologists by using the 3-point Montreal Scale. Patients were divided into 2 groups: patients treated with GDC and those treated with Matrix detachable coils. RESULTS: A total of 773 patients (461 women, 312 men; 19-80 years of age; mean, 51.2 +/- 13.2 years) with 773 ruptured aneurysms were included in the study. The rate of occlusion as determined by the treating physician was designated complete for 586 aneurysms (75.8%), neck remnant for 145 aneurysms (18.8%), and aneurysm remnant for 42 aneurysms (5.4%). The same evaluation as reported by the 2 independent reviewers was complete occlusion for 366 aneurysms (47.4%), neck remnant for 324 aneurysms (41.9%), and aneurysm remnant for 83 aneurysms (10.7%). Postoperative anatomic results were significantly linked to age but not to the technique of endovascular treatment or aneurysm characteristics (location, size, dome-to neck ratio). Results were not significantly different between the GDC and Matrix group. CONCLUSIONS: Endovascular treatment of ruptured intracranial aneurysms resulted in a high rate of satisfactory occlusion (complete occlusion and neck remnant in 89.3%). Patient age was the only factor associated with the rate of occlusion. The rate of aneurysm occlusion differed insignificantly between GDC and Matrix coils. |
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Authors:
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L Pierot; C Cognard; F Ricolfi; R Anxionnat; |
Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't Date: 2010-01-14 |
Journal Detail:
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Title: AJNR. American journal of neuroradiology Volume: 31 ISSN: 1936-959X ISO Abbreviation: AJNR Am J Neuroradiol Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-17 Completed Date: 2010-09-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003708 Medline TA: AJNR Am J Neuroradiol Country: United States |
Other Details:
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Languages: eng Pagination: 907-11 Citation Subset: IM |
Affiliation:
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Department of Neuroradiology, Maison Blanche Hospital, CHU Reims, Reims, France. lpierot@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Aneurysm, Ruptured / radiography*, surgery* Embolization, Therapeutic / instrumentation* Female France Humans Intracranial Aneurysm / radiography*, surgery* Male Middle Aged Prognosis Treatment Outcome Young Adult |
| Investigator | |
Investigator/Affiliation:
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Anne Pasco / ; Jean-François Bonneville / ; Xavier Barreau / ; Jérôme Berge / ; Patrick Courthéoux / ; Suzana Saleme / ; Emmanuel Chabert / ; Jean Gabrillargues / ; Xavier Leclerc / ; Jean-Pierre Pruvo / ; Christian Taschner / ; Olivier Lévrier / ; Alain Bonafé / ; Hubert Desal / ; Axel de Kersaint-Gilly / ; Alessandra Biondi / ; Fabrice Bonneville / ; Betty Jean / ; Nader Sourour / ; Jacques Moret / ; Charbel Mounayer / ; Michel Piotin / ; Laurent Spelle / ; Raphaël Blanc / ; Sylvie Gordon-Hardy / ; Jean-François Meder / ; Denis Trystram / ; Jacques Drouineau / ; Sophie Gallas / ; Laurent Pierot / ; Fabrice-Guy Barral / ; Luis Manera / ; Rémy Beaujeux / ; Fazel Boujan / ; Charles Arteaga / ; Christophe Cognard / ; Anne-Christine Januel / ; Philippe Tal / ; Denis Herbreteau / ; Richard Bibi / ; Yves Chau / ; Jacques Sedat / |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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