Document Detail

Imaging for suspected pulmonary embolism in pregnancy-what about the fetal dose? A comprehensive review of the literature.
MedLine Citation:
PMID:  22347929     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To give a comprehensive overview of fetal doses reported in the literature when imaging the pregnant woman with suspected pulmonary embolism (PE). METHODS: A comprehensive literature search in the PubMed, MEDLINE and EMBASE databases yielded a total of 1,687 papers that were included in the analysis and have been analysed with regard to fetal dose in suspected PE radiological imaging strategies. RESULTS: Fetal dose in chest computed tomography (CT) ranges between 0.013 and 0.026 mGy in early and 0.06-0.1 mGy in late pregnancy compared with 99mTc-MAA perfusion scintigraphy with a fetal dose of 0.1-0.6 mGy in early and 0.6-0.8 mGy in late pregnancy. (99m)Tc-aerosol ventilation scintigraphy results in 0.1-0.3 mGy. However, there is concern about female breast irradiation in CT, which is higher than in scintigraphy. CT radiation risks for breast tissue remain unclear. CONCLUSION: Knowledge of dosimetry and radiation risks is crucial in the radiological work-up of suspected PE in pregnancy. It is reasonable to reserve scintigraphy for pregnant patients with normal chest radiography findings and no history of asthma or chronic lung disease. Performing CT applying dose reduction instead of scintigraphy will minimise fetal radiation dose and maximise the diagnostic value.
Tilo Niemann; Guillaume Nicolas; Hans W Roser; Jan Müller-Brand; Georg Bongartz
Related Documents :
3126469 - The role of sonography in assessing severity of fetal anemia in rh- and kell-isoimmuniz...
1279659 - Spontaneous cessation of umbilical blood flow in the acardiac fetus of a twin pregnancy.
7892839 - The predictive value of maternal serum testing for detection of fetal anemia in red blo...
113979 - The role of fetal movements assessment in cases of severe rh immunized patients.
4015769 - Isoimmunization in pregnancy to gerbich antigen.
8507469 - Structure and composition of stereocilia cross-links in normal and hydropic cochleas of...
16601339 - Inherited thrombophilia: treatment during pregnancy.
9763059 - Influence of chemotherapy for gestational trophoblastic disease on subsequent pregnancy...
23088859 - Localisation and characterisation of uncoupling protein-2 (ucp2) in the human preterm p...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-10-2
Journal Detail:
Title:  Insights into imaging     Volume:  1     ISSN:  1869-4101     ISO Abbreviation:  Insights Imaging     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2012-2-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101532453     Medline TA:  Insights Imaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  361-372     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Technical aspects of CT imaging of the spine.
Next Document:  Imaging with non-FDG PET tracers: outlook for current clinical applications.