Document Detail


Imaging of small hepatic metastases of colorectal carcinoma: how to use superparamagnetic iron oxide-enhanced magnetic resonance imaging in the multidetector-row computed tomography age?
MedLine Citation:
PMID:  19346857     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To compare the accuracy of dynamic contrast-enhanced multidetector-row computed tomography (CT) and superparamagnetic iron oxide-enhanced magnetic resonance imaging (MRI) in the evaluation of small hepatic metastases of colorectal carcinoma. MATERIALS AND METHODS: Of 94 patients with colorectal carcinoma analyzed, 76 hepatic metastases (<2 cm) were diagnosed in 17 patients. Superparamagnetic iron oxide (SPIO)-magnetic resonance (precontrast and postcontrast MRI) and dynamic contrast-enhanced multidetector-row CT (dynamic CT [precontrast, arterial, portal-venous, and delayed phase]) were evaluated. The alternative free-response receiver operating characteristic analysis was performed, and the sensitivities and positive predictive values were analyzed. RESULTS: The Az values and sensitivities of portal-venous phase CT, dynamic CT, and SPIO-MRI (0.62/59%, 0.69/61%, and 0.67/61%) were identical. The mean positive predictive value of dynamic CT (82%) was inferior to that of SPIO-MRI (91%). CONCLUSIONS: The diagnostic ability of dynamic CT is identical to that of SPIO-MRI in Az value and sensitivity. Superparamagnetic iron oxide-MRI should be recommended only if an equivocal lesion is detected by dynamic CT.
Authors:
Utaroh Motosugi; Tomoaki Ichikawa; Hiroto Nakajima; Hironobu Sou; Mika Sano; Katsuhiro Sano; Tsutomu Araki; Hiroshi Iino; Hideki Fujii; Tadao Nakazawa
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  33     ISSN:  1532-3145     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2009 Mar-Apr
Date Detail:
Created Date:  2009-04-06     Completed Date:  2009-04-20     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  266-72     Citation Subset:  IM    
Affiliation:
Department of Radiology, University of Yamanashi, Chuo-shi, Yamanashi-ken, Japan. utaroh-motosugi@nifty.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Colorectal Neoplasms / pathology
Contrast Media / diagnostic use
False Negative Reactions
Female
Ferrosoferric Oxide
Humans
Image Enhancement / methods
Iohexol / diagnostic use
Iron / diagnostic use
Liver Neoplasms / diagnosis*,  secondary*
Magnetic Resonance Imaging / methods*
Middle Aged
Oxides / diagnostic use
Predictive Value of Tests
Sensitivity and Specificity
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Oxides; 119683-68-0/ferumoxides; 1317-61-9/Ferrosoferric Oxide; 66108-95-0/Iohexol; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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