Document Detail


Imaging of the pituitary in children with growth disorders.
MedLine Citation:
PMID:  9518219     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Magnetic resonance imaging reveals the anatomy of the pituitary and hypothalamus with unique detail. The clinical and biochemical investigation of short stature in childhood may be difficult and complex; magnetic resonance imaging of the pituitary is a non-invasive technique which can help to clarify the diagnosis of growth hormone insufficiency and to determine its cause. Most cases of growth hormone insufficiency have previously been considered to be idiopathic; in about 60% of these children, magnetic resonance imaging shows a characteristic structural abnormality which has been termed pituitary stalk interruption syndrome. The most important role of magnetic resonance imaging is in the diagnosis of destructive lesions of the hypothalamic-pituitary axis which may initially present with growth failure.
Authors:
L J Abernethy
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European journal of radiology     Volume:  26     ISSN:  0720-048X     ISO Abbreviation:  Eur J Radiol     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-03-25     Completed Date:  1998-03-25     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  102-8     Citation Subset:  IM    
Affiliation:
Department of Radiology, Royal Liverpool Childrens Hospital, Alder Hey, UK.
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MeSH Terms
Descriptor/Qualifier:
Child
Growth Disorders / etiology,  pathology*
Human Growth Hormone / deficiency
Humans
Hypothalamus / pathology
Magnetic Resonance Imaging*
Pituitary Diseases / complications,  diagnosis*
Pituitary Gland / pathology*
Chemical
Reg. No./Substance:
12629-01-5/Human Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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