| Imaging ovarian cancer and peritoneal metastases--current and emerging techniques. | |
| | |
MedLine Citation:
|
PMID: 20386556 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Peritoneal metastases are often the first presentation of ovarian malignancy. Evaluating the extent of disease critically determines tumor resectability and can also predict outcome. Standard CT, however, frequently fails to identify small sites of peritoneal spread. Moreover, it does not provide a quantitative index of disease response to cytotoxic therapy as it relies on macroscopic morphological changes in tumor volume, and does not reflect preceding molecular events in the microenvironment of the tumor. We describe the emerging role of functional imaging techniques, such as radioimmunoscintigraphy, PET/CT, diffusion-weighted MRI, dynamic contrast-enhanced MRI, and magnetic resonance spectroscopy in staging ovarian cancer and assessing treatment response. The combination of functional information with conventional anatomical visualization holds promise to accurately characterize peritoneal disease, and provides noninvasive biomarkers of therapeutic performance and patient prognosis. |
| | |
Authors:
|
Stavroula Kyriazi; Stan B Kaye; Nandita M deSouza |
Related Documents
:
|
17926036 - Evaluation of [(18)f]-choline pet/ct for staging and restaging of prostate cancer. 20624786 - Positron emission tomography/computed tomography in the management of recurrent/metasta... 18651256 - Integrated fluorine-18 fluorodeoxyglucose (18f-fdg) pet/ct compared to standard contras... 17325926 - Comparison of positron emission tomography and lymphangiography in the diagnosis of inf... 17414646 - Imaging of prostate cancer. 15390226 - In vivo 4.0-t magnetic resonance investigation of spinal cord inflammation, demyelinati... |
Publication Detail:
|
Type: Journal Article; Review Date: 2010-04-13 |
Journal Detail:
|
Title: Nature reviews. Clinical oncology Volume: 7 ISSN: 1759-4782 ISO Abbreviation: Nat Rev Clin Oncol Publication Date: 2010 Jul |
Date Detail:
|
Created Date: 2010-07-01 Completed Date: 2010-10-19 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101500077 Medline TA: Nat Rev Clin Oncol Country: England |
Other Details:
|
Languages: eng Pagination: 381-93 Citation Subset: IM |
Affiliation:
|
Section of Magnetic Resonance, Cancer Research UK and EPSRC Cancer Imaging Center, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, UK. stavroula.kyriazi@icr.ac.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Diagnostic Imaging
/
methods* Female Humans Ovarian Neoplasms / pathology*, radiography, radionuclide imaging Peritoneal Neoplasms / radiography, radionuclide imaging, secondary* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A phase 2 autologous cellular therapy trial in patients with acute, complete spinal cord injury: pra...
Next Document: Immunosuppressive properties of human umbilical cord-derived mesenchymal stem cells: role of B7-H1 a...