Document Detail


Imaging of non-small cell lung cancer of the superior sulcus: part 2: initial staging and assessment of resectability and therapeutic response.
MedLine Citation:
PMID:  18349458     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Imaging plays a crucial role in the diagnosis and staging of superior sulcus tumors, assessment of their resectability, determination of the optimal approach to disease management, and evaluation of the response to therapy. Computed tomography (CT), magnetic resonance (MR) imaging, and positron emission tomography (PET)/CT contribute important and complementary information. Whereas CT is optimal for depicting bone erosion and for staging of intrathoracic disease, MR imaging is superior for evaluating tumor extension to the intervertebral neural foramina, the spinal cord, and the brachial plexus, primarily because of the higher contrast resolution and multiplanar capability available with MR imaging technology. Use of PET/CT enables the detection of unsuspected nodal and distant metastases. However, imaging has only limited usefulness for evaluating the response of a tumor to induction therapy and detecting local recurrence, and surgical biopsy often is necessary to verify the results of therapy.
Authors:
John F Bruzzi; Ritsuko Komaki; Garrett L Walsh; Mylene T Truong; Gregory W Gladish; Reginald F Munden; Jeremy J Erasmus
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Radiographics : a review publication of the Radiological Society of North America, Inc     Volume:  28     ISSN:  1527-1323     ISO Abbreviation:  Radiographics     Publication Date:    2008 Mar-Apr
Date Detail:
Created Date:  2008-03-19     Completed Date:  2008-05-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302501     Medline TA:  Radiographics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  561-72     Citation Subset:  IM    
Copyright Information:
(c) RSNA, 2008
Affiliation:
Division of Diagnostic Imaging, Department of Radiation Oncology, M. D. Anderson Cancer Center, Houston, Tex., USA. John.Bruzzi@hse.ie
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MeSH Terms
Descriptor/Qualifier:
Carcinoma, Non-Small-Cell Lung / pathology*,  surgery*
Combined Modality Therapy
Contrast Media
Fluorodeoxyglucose F18 / diagnostic use
Humans
Lung Neoplasms / pathology*,  surgery*
Lymphatic Metastasis
Magnetic Resonance Imaging
Neoplasm Recurrence, Local / diagnosis
Neoplasm Staging
Positron-Emission Tomography
Radiography, Thoracic
Radiopharmaceuticals / diagnostic use
Radiotherapy, Adjuvant
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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