Document Detail


Imaging and molecular biomarkers of vulnerable atheromatous plaques.
MedLine Citation:
PMID:  20477458     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Rupture of a vulnerable atherosclerotic plaque is the main cause of acute coronary syndromes, myocardial infarction and death. Identification of biomarkers that accurately predict the risk of plaque rupture may be a means to establish and monitor response to therapeutic intervention. This review focuses on recent advances for the use of circulating molecular biomarkers and imaging modalities to assess atherosclerotic vulnerable plaques in both preclinical models and clinical conditions.
Authors:
Xinkang Wang; J Lynn Rutkowsky; Giora Z Feuerstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomarkers in medicine     Volume:  1     ISSN:  1752-0371     ISO Abbreviation:  Biomark Med     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2010-05-18     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101312535     Medline TA:  Biomark Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  23-35     Citation Subset:  -    
Affiliation:
Wyeth Research, Translational Medicine, 500 Arcola Road, S2324, Collegeville, PA 19426, USA. wangx8@wyeth.com
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