| Imaging manifestations of progressive multifocal leukoencephalopathy. | |
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MedLine Citation:
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PMID: 20451009 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by reactivation of JC virus in immunosuppressed patients. The diagnosis is usually suggested on imaging and confirmed by cerebrospinal fluid polymerase chain reaction (PCR) for JC virus DNA. In this article, we review the imaging manifestations of PML on computed tomography (CT), magnetic resonance imaging (MRI), diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), MR spectroscopy, single photon-emission computed tomography (SPECT) and positron-emission tomography (PET), and outline the role of imaging in follow-up and prognostication. |
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Authors:
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R Shah; A K Bag; P R Chapman; J K Curé |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinical radiology Volume: 65 ISSN: 1365-229X ISO Abbreviation: Clin Radiol Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-10 Completed Date: 2010-09-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1306016 Medline TA: Clin Radiol Country: England |
Other Details:
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Languages: eng Pagination: 431-9 Citation Subset: IM |
Copyright Information:
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Copyright 2010 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Division of Neuroradiology, Department of Diagnostic Radiology, University of Alabama at Birmingham, Birmingham, Alabama, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Diffusion Magnetic Resonance Imaging
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methods Diffusion Tensor Imaging / methods Humans Immunocompromised Host Leukoencephalopathy, Progressive Multifocal / diagnosis* Magnetic Resonance Spectroscopy / methods Positron-Emission Tomography / methods Prognosis Tomography, Emission-Computed, Single-Photon / methods United States |
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