| Imaging macrophage development and fate in atherosclerosis and myocardial infarction. | |
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MedLine Citation:
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PMID: 23207281 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Macrophages are central regulators of disease progression in both atherosclerosis and myocardial infarction (MI). In atherosclerosis, macrophages are the dominant leukocyte population that influences lesional development. In MI, which is caused by atherosclerosis, macrophages accumulate readily and have important roles in inflammation and healing. Molecular imaging has grown considerably as a field and can reveal biological process at the molecular, cellular and tissue levels. Here, we explore how various imaging modalities, from intravital microscopy in mice to organ-level imaging in patients, are contributing to our understanding of macrophages and their progenitors in cardiovascular disease.Immunology and Cell Biology advance online publication, 4 December 2012; doi:10.1038/icb.2012.72. |
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Authors:
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Filip K Swirski; Matthias Nahrendorf |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-04 |
Journal Detail:
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Title: Immunology and cell biology Volume: - ISSN: 1440-1711 ISO Abbreviation: Immunol. Cell Biol. Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8706300 Medline TA: Immunol Cell Biol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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