| Imaging indexes of activity and severity for Crohn's disease: current status and future trends. | |
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MedLine Citation:
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PMID: 22072290 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Cross-sectional imaging techniques, including ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI) are increasingly used for evaluation of Crohn's disease (CD). AIM: To review the accuracy of cross-sectional imaging indexes for measurement of disease activity and severity in patients with CD, and to evaluate its applicability on daily clinical practice and research. METHODS: Relevant publications were identified by literature search, and selected based on predefined quality parameters, including a sample size and reference standard. Nineteen publications were chosen. RESULTS: The US-based indexes of activity showed high correlation with reference standard indexes. There is a good or very good agreement between the MR-based indexes and the reference standard when the comparison is limited to small segments of intestine. Significant discrepancies have been found between indexes that evaluate the colon. Only one CT-based index was included. The main strengths and weaknesses of the indexes, according to its design, are discussed. CONCLUSION: Standardization of image acquisition protocols and patient preparation should be procured, especially for MRI. In daily practice, a simple, semi-quantitative index providing relevant information on disease activity and severity is preferable. For research purposes, a precise and reproducible index should be mandatory. |
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Authors:
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Jordi Rimola; Ingrid Ordás; Sonia Rodríguez; Elena Ricart; Julián Panés |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-10 |
Journal Detail:
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Title: Abdominal imaging Volume: - ISSN: 1432-0509 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9303672 Medline TA: Abdom Imaging Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology, Centro de Investigaciones Biomédicas en Red, enfermedades hepáticas y digestivas (CIBER-ehd), IDIBAPS, Hospital Clínic of Barcelona, Villarroel 170, 08036, Barcelona, Spain, jrimola@clinic.ub.es. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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