| Imaging in follicular NHL. | |
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MedLine Citation:
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PMID: 21658616 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Imaging contributes to management of follicular lymphoma (FL) through guiding biopsy, determining disease stage and assessing therapeutic response. Molecular imaging with positron emission tomography (PET), especially when combined with computer tomography (PET/CT), is more accurate than conventional imaging and extends the role of imaging to lesion characterisation, including non-invasive assessment of high-grade transformation. There is strong data to support the use of FDG PET/CT for primary staging, resulting in significant management change. In patients with early stage follicular lymphoma (stage I or II), there is a clear role for PET/CT to avoid futile involved-field radiotherapy in patients with widespread disease and to optimise the treatment field in patients with confirmed localised disease. For restaging, use of PET/CT allows discrimination between scar tissue and viable tumour in residual masses. Molecular imaging is likely to play an increasing role in selection of patients for specific treatments and in prognostic stratification. |
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Authors:
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M S Hofman; R J Hicks |
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Publication Detail:
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Type: Journal Article Date: 2011-05-04 |
Journal Detail:
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Title: Best practice & research. Clinical haematology Volume: 24 ISSN: 1532-1924 ISO Abbreviation: Best Pract Res Clin Haematol Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-06-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101120659 Medline TA: Best Pract Res Clin Haematol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 165-77 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
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Centre for Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Australia; University of Melbourne, Melbourne, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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