| Imaging in acute ischaemic stroke: essential for modern stroke care. | |
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MedLine Citation:
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PMID: 20634251 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Stroke is the second most common cause of death worldwide and the third most common in the UK. 'Time is brain' in ischaemic stroke; early reperfusion has been shown to lead to improved clinical outcomes, yet the majority of patients with acute stroke do not attend in time for thrombolysis as it is currently licensed, hence the interest in trials extending the therapeutic window. Defining the ischaemic penumbra is of crucial importance in choosing the appropriate patients for thrombolytic therapy who attend outside the optimal therapeutic window. Integrated stroke imaging, including demonstration of potentially salvageable tissue with either MR perfusion/diffusion studies or CT perfusion, is increasingly likely to play a central role in future management strategies and widening of the potential therapeutic window. This review highlights the basic imaging findings of acute stroke and discusses the role of advanced CT and MR techniques as well as options for vascular imaging. |
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Authors:
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Daniel J Warren; Rachel Musson; Daniel J A Connolly; Paul D Griffiths; Nigel Hoggard |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Postgraduate medical journal Volume: 86 ISSN: 1469-0756 ISO Abbreviation: Postgrad Med J Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-16 Completed Date: 2010-12-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0234135 Medline TA: Postgrad Med J Country: England |
Other Details:
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Languages: eng Pagination: 409-18 Citation Subset: IM |
Affiliation:
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Radiology Department, Royal Hallamshire Hospital, Sheffield NHS Teaching Hospitals Trust, Sheffield S10 2JF, UK. daniel.warren@sth.nhs.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Brain Ischemia / diagnosis* Humans Magnetic Resonance Angiography / methods Stroke / diagnosis* Tomography, X-Ray Computed / methods |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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