Document Detail


Imaging in Graves' orbitopathy.
MedLine Citation:
PMID:  19839878     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In patients with Graves' orbitopathy, magnetic resonance imaging (MRI) is a useful tool to distinguish the acute inflammatory active disease in demonstrating interstitial edema within the extraocular muscles on coronal TIRM-sequences from fibrotic, inactive endstage disease. MRI is the modality of choice to identify active inflammatory changes in order to decide on possible immunomodulatory treatment response. However, MRI should be considered in atypical cases as in asymmetrical orbital involvement, to exclude other orbital pathologies and to confirm the clinical suspicion of apical optic nerve compression in Graves' orbitopathy. Computed tomography (CT) provides precise imaging of the osseous periorbital structures and does not reveal information on the disease activity in most cases. It is therefore the method of choice to plan CT-guided orbital decompression surgery in the inactive phase of disease.
Authors:
Eberhard Kirsch; Georg von Arx; Beat Hammer
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Orbit (Amsterdam, Netherlands)     Volume:  28     ISSN:  1744-5108     ISO Abbreviation:  Orbit     Publication Date:  2009  
Date Detail:
Created Date:  2009-10-20     Completed Date:  2010-02-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8301221     Medline TA:  Orbit     Country:  England    
Other Details:
Languages:  eng     Pagination:  219-25     Citation Subset:  IM    
Affiliation:
Neuroradiology, Hirslanden Clinic Aarau, Schaenisweg, Aarau, Switzerland. eberhard.kirsch@hirslanden.ch
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MeSH Terms
Descriptor/Qualifier:
Contrast Media
Diagnosis, Differential
Diagnostic Imaging*
Graves Disease / diagnosis*
Humans
Magnetic Resonance Imaging / methods
Radiopharmaceuticals / diagnostic use
Tomography, Emission-Computed
Tomography, X-Ray Computed / methods
Ultrasonography / methods
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Radiopharmaceuticals

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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