Document Detail


Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma.
MedLine Citation:
PMID:  19963312     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The microcirculation is essential for delivery of oxygen and nutrients to tissue. However, the human microvascular response to cardiopulmonary resuscitation (CPR) is unknown. We report on the first use of sidestream dark field imaging to assess the human microcirculation during CPR with a mechanical chest compression/decompression device (mCPR). mCPR was able to provide microvascular perfusion. Capillary flow persisted even during brief mCPR interruption. However, indices of microvascular perfusion were low and improved vastly after return of spontaneous circulation. Microvascular perfusion was relatively independent from blood pressure. The microcirculation may be a useful monitor for determining the adequacy of CPR.
Authors:
Paul W G Elbers; Antonius J Craenen; Antoine Driessen; Marco C Stehouwer; Luuk Munsterman; Miranda Prins; Mat van Iterson; Peter Bruins; Can Ince
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-12-05
Journal Detail:
Title:  Resuscitation     Volume:  81     ISSN:  1873-1570     ISO Abbreviation:  Resuscitation     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-01     Completed Date:  2010-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0332173     Medline TA:  Resuscitation     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  123-5     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Anesthesia, Intensive Care and Pain Management, St. Antonius Ziekenhuis, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands. info@acidbase.org
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Cardiopulmonary Resuscitation*
Fatal Outcome
Humans
Hypothermia / physiopathology,  therapy*
Male
Microcirculation*
Microscopy, Polarization*
Near Drowning / physiopathology,  therapy*
Rewarming / methods*
Comments/Corrections
Comment In:
Resuscitation. 2010 Jan;81(1):5   [PMID:  20004508 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Conceptualizing the healthscape: Contributions of time geography, location technologies and spatial ...
Next Document:  Bioactive nanofibers for fibroblastic differentiation of mesenchymal precursor cells for ligament/te...