| Imaging of forward light-scatter by opacified posterior capsules isolated from pseudophakic donor eyes. | |
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MedLine Citation:
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PMID: 21622703 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Purpose: Posterior capsule opacification (PCO) degrades visual function by reducing visual acuity, but also by increasing intra-ocular light-scatter. We used an in-vitro model to elucidate the effect of PCO-morphology on light-scatter and its functional aspect, as can be assessed with straylight measurement. Methods: Forward PCO-scatter by opacified capsular bags was recorded with a goniometer and camera. The camera position mimicked the anatomical position of retinal photoreceptors; the camera recorded the scattered light that the photoreceptors would sense in an in-vivo situation. Scattered light was recorded at different wavelengths and scatter angles, which were divided into a near (1° < = 7°) and far ( > 7°) large-angle domain. Using scattered light, the camera produced grayscale PCO-images. The nature of the angular dependence of PCO-scatter was compared to that of scatter in the normal eye, by rescaling PCO-images relative to the normal eye's point-spread function. Results: The scattered light images closely followed PCO-severity. The angular dependence of PCO-scatter resembled that of scatter in the normal eye , irrespective of severity and PCO-type. PCO shows the type of wavelength dependence that is normal for small particles: monotonically decreasing with increasing wavelength. At the near large-angle domain, the angular dependence of PCO-scatter and scatter in the normal eye resembled less closely. Conclusions: Surprisingly, PCO-scatter and scatter in the normal eye have similar underlying scattering processes. However, data obtained at the near large-angle domain demonstrates that, apart from scatter, PCO may also have a refractile component, which is most pronounced in pearl-type PCO. |
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Authors:
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Maartje C J van Bree; Ivanka J E van der Meulen; Luuk Franssen; Joris E Coppens; Nicolaas J Reus; Bart L M Zijlmans; Thomas J T P van den Berg |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-27 |
Journal Detail:
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Title: Investigative ophthalmology & visual science Volume: - ISSN: 1552-5783 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Rotterdam Ophthalmic Institute, Schiedamse Vest 160, 3011 BH Rotterdam, The Netherlands. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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