Document Detail


Imaging findings of congenital glaucoma in Opitz syndrome.
MedLine Citation:
PMID:  18310233     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Opitz syndrome is a rare autosomal recessive disorder of cholesterol metabolism associated with mental retardation and multiple congenital malformations. It is also uncommonly associated with congenital glaucoma. We describe the orbital findings on CT in this rare case of a patient with Opitz syndrome who presented with congenital glaucoma, with a review of the literature. The CT findings of congenital glaucoma, which have not been described before in the literature, are also discussed. It is important for the radiologist to be aware of this rare association. It is also important to be aware of the findings of congenital glaucoma on CT because patients with Opitz syndrome and other syndromes associated with learning difficulties may not present with typical clinical features of glaucoma. A high index of suspicion will lead to a correct diagnosis and earlier intervention.
Authors:
A K Choudhary; B Jha
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-02-29
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  29     ISSN:  1936-959X     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-14     Completed Date:  2008-06-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1003-5     Citation Subset:  IM    
Affiliation:
Department of Radiology, Hershey Medical Center, Hershey, PA 17036, USA. achoudhary@hmc.psu.edu
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MeSH Terms
Descriptor/Qualifier:
Child
Female
Glaucoma / congenital*,  radiography*
Humans
Smith-Lemli-Opitz Syndrome / radiography*
Tomography, X-Ray Computed*

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