| Imaging characteristics of extrapulmonary tuberculosis lesions on dual time point imaging (DTPI) of FDG PET/CT. | |
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MedLine Citation:
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PMID: 22141602 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Introduction: This study aimed to evaluate the diagnostic value of dual time point imaging (DTPI) of 18F-fluorodeoxyglucose (FDG) positron emission tomography/CT (PET/CT) for detecting the infective lesions in patients with extrapulmonary tuberculosis (EPTB). Methods: Eleven patients were consecutively recruited and evaluated. After the intravenous injection of 369 ± 153 MBq of FDG, all patients underwent FDG PET/CT imaging at two different time points: early scan at 57 ± 23 min and delayed scan at 136 ± 42 min. The maximum standardized uptake values (SUVmax) were recorded for both time points (early scan: SUVmax1 and delayed scan: SUVmax2). Results: In total, 30 lesions were detected. The SUVmax2 in 22 of the lesions in confirmed EPTB patients were significantly higher than the SUVmax1 (7.9 ± 3.2 vs. 6.8 ± 2.5; P = 0.001). The SUVmax for another eight non-EPTB lesions also showed a significant increasing pattern of change (6.2 ± 2.6 vs. 6.5 ± 2.8; P = 0.044). However, there was insignificant difference between the mean percentage difference of SUVmax (%ΔSUVmax) of EPTB and non-EPTB lesions (P = 0.06). Conclusion: Our study demonstrates that early whole body PET/CT imaging may be sufficient for the detection of the EPTB lesions and DTPI of PET/CT may also not be a useful technique in differentiating between EPTB and non-EPTB lesions. However, our findings are based on a limited number of patients, and therefore, further investigations in larger series of patients are warranted. |
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Authors:
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Hairil Rashmizal Abdul Razak; Moshi Geso; Noraini Abdul Rahim; Abdul Jalil Nordin |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of medical imaging and radiation oncology Volume: 55 ISSN: 1754-9485 ISO Abbreviation: J Med Imaging Radiat Oncol Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101469340 Medline TA: J Med Imaging Radiat Oncol Country: Australia |
Other Details:
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Languages: eng Pagination: 556-62 Citation Subset: IM |
Copyright Information:
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© 2011 The Authors. Journal of Medical Imaging and Radiation Oncology © 2011 The Royal Australian and New Zealand College of Radiologists. |
Affiliation:
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Discipline of Medical Radiations, School of Medical Sciences, Bundoora West Campus, RMIT University, Victoria, Australia Diagnostic Imaging Department, Serdang Hospital, Kajang Nuclear Imaging Centre, Faculty of Medicine and Health Sciences, University Putra Malaysia, Serdang, Selangor, Malaysia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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