Document Detail


Imaging of cerebral vasculitis.
MedLine Citation:
PMID:  18705942     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: In young patients, vasculitic stenoses of cerebral blood vessels are an important cause of cerebral ischaemia. Diagnosis may prove very difficult. SUMMARY OF REVIEW: The diagnostic process is usually initiated by the detection of brain lesions consistent with cerebral vasculitis. Multiple infarcts of various ages in more than one vascular territory are thought to be suggestive of a vascular inflammatory disease. The next step in the imaging of patients with suspected vasculitis is the search for an underlying vascular stenosis. Today, magnetic resonance angiography is the principal modality for the investigation of patients thought to have intracranial stenoses. At 1.5 T, only large brain arteries can be imaged with a high diagnostic accuracy. Intraarterial DSA remains an indispensable tool for the investigation of medium and small brain artery stenoses. CONCLUSIONS: However, contrast-enhanced magnetic resonance imaging may be able to demonstrate wall thickening and contrast uptake in large cerebral arteries, obviating biopsy in patients with basal vasculitis.
Authors:
Wilhelm Küker
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of stroke : official journal of the International Stroke Society     Volume:  2     ISSN:  1747-4949     ISO Abbreviation:  -     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2008-08-18     Completed Date:  2008-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101274068     Medline TA:  Int J Stroke     Country:  England    
Other Details:
Languages:  eng     Pagination:  184-90     Citation Subset:  IM    
Affiliation:
Department of Neuroradiology, West Wing, The John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, UK. Wilhelm.Kuker@ndm.ox.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Brain / blood supply*
Humans
Magnetic Resonance Imaging* / methods
Vasculitis, Central Nervous System / classification,  diagnosis*

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