| Imaging of cerebral perfusion in acute stroke. | |
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MedLine Citation:
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PMID: 16197824 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Rapid imaging of cerebral perfusion in acute stroke is needed for timely triage of patients for thrombolytic therapy. Accurate quantitative perfusion imaging is required for proper assessment of penumbral brain parenchyma truly at risk for extension of infarction from the irreversible core infarction. CT and MRI techniques offer rapidity and availability for acute stroke imaging, including that of cerebral perfusion. CT perfusion techniques are readily available, but suffer from limited brain coverage of present multislice scanners. MRI offers whole brain coverage, but suffers from less availability and higher cost than CT. Presently, development is directed towards increasing the quantitative accuracy of cerebral perfusion imaging and validation of surrogate parameters, such as time to peak (TTP). In the future, the need for rapid and frequent assessment of cerebral perfusion and its metabolic correlates, with minimal or no radiation, will probably be met by MRI. |
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Authors:
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John M Gomori; José E Cohen |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Neurological research Volume: 27 Suppl 1 ISSN: 0161-6412 ISO Abbreviation: Neurol. Res. Publication Date: 2005 |
Date Detail:
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Created Date: 2005-10-03 Completed Date: 2005-11-08 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7905298 Medline TA: Neurol Res Country: England |
Other Details:
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Languages: eng Pagination: S50-2 Citation Subset: IM |
Affiliation:
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Division of Endovascular Neurosurgery and Interventional Neuroradiology, Hadassah Ein Kerem University Hospital, Jerusalem, Israel. gomori@md.huji.ac.il |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cerebrovascular Circulation
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physiology* Humans Magnetic Resonance Imaging Stroke / diagnosis, physiopathology, therapy* Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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