Document Detail

Imaging of calcified coronary arteries with multislice computed tomography.
MedLine Citation:
PMID:  16868107     Owner:  NLM     Status:  MEDLINE    
Reliable noninvasive detection of coronary artery disease is a prime goal in clinical cardiology. The aim of this study was to investigate the accuracy of multislice computed tomography in detecting coronary artery disease in correlation to the calcium score. Fifty patients with 61 stenoses > 50% and 41 occlusions underwent multislice computed tomography and conventional coronary angiography. Calcium scoring was calculated for the total coronary artery territory and patients were divided into 3 groups based on this score. Multislice computed tomography visualized 89% (365/500) of all coronary segments. The sensitivity and specificity for detection of stenoses > 50% or occlusion was 47%-92%, and 97%-100% for the calcium score. Forty of 500 segments were underestimated by multislice computed tomography, of which 39 were in the group with a calcium score > 400. Multislice computed tomography allows noninvasive angiographic evaluation of coronary artery disease with high diagnostic accuracy. However, the method strongly depends on the degree of vascular calcification and underestimates the degree of stenosis according to the calcium score. This new technology holds promise for noninvasive risk assessment in patients with known or suspected coronary artery disease.
Thomas Wittlinger; Ivo Martinovic; Rainer Moosdorf; Anton Moritz
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Asian cardiovascular & thoracic annals     Volume:  14     ISSN:  1816-5370     ISO Abbreviation:  Asian Cardiovasc Thorac Ann     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-26     Completed Date:  2008-05-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9503417     Medline TA:  Asian Cardiovasc Thorac Ann     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  321-7     Citation Subset:  IM    
Department of Thoracic and Cardiovascular Surgery, University Hospital, Theodor-Stern Kai 7, 60590 Frankfurt/Main, Germany.
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MeSH Terms
Calcinosis / radiography*
Coronary Angiography
Coronary Artery Disease / radiography*
Coronary Stenosis / radiography*
Predictive Value of Tests
Sensitivity and Specificity
Tomography, X-Ray Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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