Document Detail


Imaging Periprosthetic Osteolysis Around Total Knee Arthroplasties Using a Human Cadaver Model.
MedLine Citation:
PMID:  22085797     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We examined the sensitivity and accuracy of measuring osteolysis around total knee arthroplasty (TKA) on radiographs, computed tomography (CT), and magnetic resonance imaging (MRI) in a cadaver model. Fifty-four simulated osteolytic defects ranging from 0.7 to 14 cm(3) were created in 6 cadaver knees implanted with either a cemented or an uncemented TKA. Three blinded investigators assessed the presence, location, and volume of defects on radiographs and CT and MRI scans with metal reduction protocols. Both CT and MRI had significantly higher sensitivities and specificities than did plain radiographs (P < .005). Overall, there was no difference in the accuracy of defect volume measurements between CT and MRI (P = .574). This study demonstrates the limitations of radiographs and the high sensitivity and specificity of both CT and MRI in assessing osteolysis around TKA.
Authors:
Lucian B Solomon; Roumen B Stamenkov; Andrew J Macdonald; Nammon Yaikwavong; Susan D Neale; Mary J Moss; Donald W Howie
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-14
Journal Detail:
Title:  The Journal of arthroplasty     Volume:  -     ISSN:  1532-8406     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8703515     Medline TA:  J Arthroplasty     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Crown Copyright © 2011. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Adelaide, Australia; Discipline of Orthopaedics and Trauma, University of Adelaide, Adelaide, Australia; Discipline of Anatomy and Pathology, University of Adelaide, Adelaide, Australia.
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