| Imaging of brain metastases of bronchial carcinomas with 7 T MRI - initial results. | |
| | |
MedLine Citation:
|
PMID: 20544578 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To compare the depiction of brain metastases of bronchial carcinomas on susceptibility-weighted and contrast-enhanced images with 7 T and at 1.5 T MRI. MATERIALS AND METHODS: Twelve patients with brain metastases of bronchial carcinomas underwent 7 T and 1.5 T MRI. Minimum intensity projections (MinIP) of a 1.5 T SWI sequence (voxel size = 0.9 x 0.9 x 2.0 mm(3)) were compared to 7 T SWI MinIPs (voxel size = 0.4 x 0.4 x 1.5 mm(3)). A T 1-w 3D MPRAGE at 1.5 T (voxel size = 1 x 1 x 1 mm(3) after double-dose (DD) gadoterate meglumine, Gd-DOTA) was compared to a 7 T MPRAGE sequence (voxel size = 0.7 x 0.7 x x 0.7 mm(3), single dose (SD) Gd-DOTA) in all patients, and to DD Gd-DOTA in 6 patients after a 10 minute delay. The number of intracranial microhemorrhages in SWI MinIPs and the number of contrast-enhancing metastases in MPRAGE images were compared in each patient grouped into three size ranges (< or = 2 mm, > 2 mm and < 6 mm, > or = 6 mm) by two radiologists in consensus. RESULTS: In all 12 patients the 7 T SWI with spatially higher resolution allowed the identification of 87 versus 67 cerebral microhemorrhages at 1.5 T. 7 T T 1-w images after SD Gd-DOTA depicted 198 brain metastases versus 238 at 1.5 T after DD Gd-DOTA. After doubling the contrast dose in six patients, 4 additional brain metastases were identified at 7 T. CONCLUSION: Our preliminary results indicate that despite the higher spatial resolution the detection of brain metastases on 7 T MPRAGE images is almost equal to 1.5 T MPRAGE images. The 7 T SWI sequence with spatially higher resolution allowed the detection of 20 % more microhemorrhages in brain metastases compared to the 1.5 T SWI sequence. |
| | |
Authors:
|
C Mönninghoff; S Maderwald; J M Theysohn; P Schütt; T Gauler; O Kraff; M E Ladd; S C Ladd; I Wanke |
Related Documents
:
|
20882618 - Late gadolinium enhancement of acute myocardial infarction in mice at 7t: cine-flash ve... 19160028 - Noninvasive monitoring of hpma copolymer-rgdfk conjugates by magnetic resonance imaging. 2002098 - Mr fat suppression combined with gd-dtpa enhancement in optic neuritis and perineuritis. 7820018 - Mri manifestations of gastrointestinal lymphoma. 21381798 - Induction of luciferase activity under the control of an hsp70 promoter using high-inte... 18434058 - Pharmacokinetic mr analysis of the cartilage is influenced by field strength. |
Publication Detail:
|
Type: Journal Article Date: 2010-06-11 |
Journal Detail:
|
Title: RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin Volume: 182 ISSN: 1438-9010 ISO Abbreviation: Rofo Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-20 Completed Date: 2010-09-22 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7507497 Medline TA: Rofo Country: Germany |
Other Details:
|
Languages: eng Pagination: 764-72 Citation Subset: IM |
Copyright Information:
|
Georg Thieme Verlag KG Stuttgart, New York. |
Affiliation:
|
Institut für diagnostische und interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen. christoph.moenninghoff@uk-essen.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Brain / pathology Brain Neoplasms / diagnosis, pathology, secondary* Carcinoma, Bronchogenic / diagnosis, pathology, secondary* Carcinoma, Non-Small-Cell Lung / diagnosis, pathology, secondary* Carcinoma, Small Cell / diagnosis, pathology, secondary* Contrast Media / administration & dosage Dose-Response Relationship, Drug Female Heterocyclic Compounds / diagnostic use Humans Image Enhancement* Image Processing, Computer-Assisted* Infusions, Intravenous Intracranial Hemorrhages / diagnosis Lung Neoplasms / diagnosis*, pathology Magnetic Resonance Imaging* Male Middle Aged Neoplasm Staging Organometallic Compounds / diagnostic use Prospective Studies Sensitivity and Specificity |
| Chemical | |
Reg. No./Substance:
|
0/Contrast Media; 0/Heterocyclic Compounds; 0/Organometallic Compounds; 92923-44-9/gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The Frontal-Impact Response of a Booster-Seated Child-Size PMHS.
Next Document: Consensus Meeting of Course Directors in Breast Imaging, 9 May 2009, in Frankfurt am Main - Topic: M...