| Imaged deconvolution: a method for extracting high-resolution NMR spectra from inhomogeneous fields. | |
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MedLine Citation:
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PMID: 17196412 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We present a novel method for obtaining high resolution NMR spectra in the presence of grossly inhomogeneous magnetic fields, such as those encountered in one-sided access NMR. Our method combines the well-known principle of reference deconvolution with NMR imaging in order to resolve spectral features with frequency resolution orders of magnitude smaller than the prevailing line-broadening due to field inhomogeneity. We demonstrate that, in cases of inhomogeneous field line-broadening more than an order of magnitude larger than the spectral features to be resolved, rather than performing reference deconvolution on the sample as a whole, it is more favourable in terms of SNR to divide the target region of a sample into smaller sub-regions, by means of chemical shift imaging, and then to perform reference deconvolution on the individual sub-region spectra, finally summing the results In this way, significant resolution enhancements can be obtained in the presence of severe magnetic field inhomogeneity without an unacceptable loss in SNR. |
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Authors:
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Meghan E Halse; Paul T Callaghan |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-12-28 |
Journal Detail:
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Title: Journal of magnetic resonance (San Diego, Calif. : 1997) Volume: 185 ISSN: 1090-7807 ISO Abbreviation: J. Magn. Reson. Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-04-02 Completed Date: 2007-05-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9707935 Medline TA: J Magn Reson Country: United States |
Other Details:
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Languages: eng Pagination: 130-7 Citation Subset: IM |
Affiliation:
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MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Sciences, Victoria University of Wellington, Wellington 6001, New Zealand. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms* Anisotropy Computer Simulation Electromagnetic Fields Image Interpretation, Computer-Assisted / methods* Magnetic Resonance Spectroscopy / methods* Models, Chemical* Models, Molecular* Sensitivity and Specificity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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