Document Detail

Image fusion of coronary CT angiography and cardiac perfusion MRI: a pilot study.
MedLine Citation:
PMID:  20204639     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To develop a tool for the image fusion of computed tomography coronary angiography (CTCA) and cardiac magnetic resonance imaging (CMR). METHODS: Surface representations and volume-rendered images from fused CTCA/CMR data of five patients with significant coronary artery disease (CAD) on CTCA and perfusion deficits on CMR were generated using a newly developed software prototype. The spatial relationship of significant coronary artery stenosis at CTCA and myocardial defects at CMR was evaluated. RESULTS: Registration of CTCA and CMR images was possible in all patients. The comprehensive three-dimensional visualisation of fused CTCA and CMR data accurately demonstrated the relationship between coronary artery stenoses and myocardial defects in all patients. CONCLUSION: The introduced tool enables image fusion of CTCA and CMR data sets and allows for correct superposition of the coronary arteries derived from CTCA onto the corresponding myocardial segments derived from CMR. The method facilitates the comprehensive assessment of the functionally relevant CAD by the exact allocation of culprit coronary stenoses to corresponding myocardial defects at a low radiation dose.
Paul Stolzmann; Hatem Alkadhi; Hans Scheffel; Anja Hennemuth; Caroline Kuehnel; Stephan Baumueller; Sebastian Kozerke; Volkmar Falk; Borut Marincek; Olivio F Donati
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-03-04
Journal Detail:
Title:  European radiology     Volume:  20     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-07     Completed Date:  2010-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1174-9     Citation Subset:  IM    
Institute of Diagnostic Radiology, University Hospital Zurich, Zurich, Switzerland.
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MeSH Terms
Cardiac-Gated Imaging Techniques / methods*
Contrast Media
Coronary Angiography / methods*
Coronary Artery Disease / diagnosis*,  radiography
Image Enhancement / methods*
Image Processing, Computer-Assisted / methods*
Imaging, Three-Dimensional
Iohexol / analogs & derivatives,  diagnostic use
Magnetic Resonance Imaging / methods*
Middle Aged
Pilot Projects
Tomography, X-Ray Computed / methods*
Reg. No./Substance:
0/Contrast Media; 66108-95-0/Iohexol; 73334-07-3/iopromide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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