Document Detail


Image analysis of nail fold capillaries in patients with Raynaud's phenomenon.
MedLine Citation:
PMID:  8575220     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Videograph images of nail fold capillaries in patients with Raynaud's phenomenon were analyzed, and capillary patterns were defined using standardized canonical discriminant analysis. Of sixty-eight patients with Raynaud's phenomenon, forty-nine (72 percent) showed a systemic sclerosis pattern and nineteen (28 percent) showed a normal pattern. The systemic sclerosis type capillary pattern significantly correlated not only with secondary Raynaud's syndrome but also with sclerodactyly, telangiectasia, and antinuclear antibody. This study confirms the value of nail fold capillary microscopy as a noninvasive technique for the examination of the cutaneous microcirculation in vivo. We should continue to evaluate the patients with Raynaud's phenomenon who showed systemic sclerosis pattern abnormality to determine if these patients would show a progression to systemic sclerosis or not.
Authors:
T Ohtsuka; A Yamakage; T Tamura
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cutis; cutaneous medicine for the practitioner     Volume:  56     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  1995 Oct 
Date Detail:
Created Date:  1996-03-13     Completed Date:  1996-03-13     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  215-8     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Gunma University School of Medicine, Maebashi, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Capillaries / pathology*
Female
Humans
Image Processing, Computer-Assisted / methods
Male
Microscopy
Middle Aged
Nails / blood supply*,  pathology
Raynaud Disease / diagnosis*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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