Document Detail


Image analysis in time-resolved large field of view 3D MR-angiography at 3T.
MedLine Citation:
PMID:  18972352     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To qualitatively and quantitatively evaluate the image quality in accelerated time-resolved 3D contrast-enhanced MR angiography (tr-CE-MRA) at 3T. MATERIALS AND METHODS: In all, 113 MRA were performed in 107 patients on a 3T MR system after written informed consent and approval by the ethics committee. Twenty consecutive thoracic (n=87) or craniocervical (n=26) 3D data volumes were acquired. The timeframes with maximum arterial and venous contrast were determined and a total of 663 arterial and venous segments were analyzed by two blinded observers. Diagnostic image quality was graded by applying a 0 (low) to 3 (excellent) scale. Additionally, local signal-to-noise (SNR) and contrast-to-noise ratios (relative CNR) were evaluated. RESULTS: Tr-CE-MRA was successfully performed in all patients. Good to excellent image quality (2.42+/-0.31) was observed in all individuals with preserved discrimination of arteries (2.43+/-0.48) and veins (2.20+/-0.56). Minor image degradation due to artifacts (2.62+/-0.25) and constantly high vascular signal and contrast were detected. There was a significant superiority of coronal orientation during thoracic MRA (P<0.05). In 18 cases tr-CE-MRA provided additional information on vascular pathologies. CONCLUSION: Large field of view tr-CE-MRA enables constantly high-quality thoracic and craniocervical angiographies. In addition, the dynamics of tr-CE-MRA can offer additional information on vascular pathologies.
Authors:
Alex Frydrychowicz; Thorsten A Bley; Zahra Abdullah Zadeh; Andreas Harloff; Jan T Winterer; Jürgen Hennig; Mathias Langer; Michael Markl
Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  28     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-03     Completed Date:  2009-01-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1116-24     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2008 Wiley-Liss, Inc.
Affiliation:
Department of Diagnostic Radiology and Medical Physics, University Hospital Freiburg, Germany. alex.frydrychowicz@uniklinik-freiburg.de
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Algorithms*
Cerebral Angiography / methods*
Female
Humans
Image Enhancement / methods*
Image Interpretation, Computer-Assisted / methods*
Imaging, Three-Dimensional / methods*
Magnetic Resonance Angiography / methods*
Male
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Thoracic Arteries / pathology*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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