Document Detail


Illicit use of buprenorphine in a community sample of young adult non-medical users of pharmaceutical opioids.
MedLine Citation:
PMID:  22036303     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: There is growing evidence about illicit use of buprenorphine in the U.S. The study aims to: (1) identify prevalence and predictors of illicit buprenorphine use in a community sample of 396 young adult (18-23 years old) non-medical users of pharmaceutical opioids and (2) describe knowledge, attitudes and behaviors linked to illicit buprenorphine use as reported by a qualitative sub-sample (n=51).
METHODS: Participants were recruited using respondent-driven sampling. Qualitative interview participants were selected from the larger sample. The sample (n=396) was 54% male and 50% white; 7.8% reported lifetime illicit use of buprenorphine.
RESULTS: Logistic regression analysis results indicate that white ethnicity, intranasal inhalation of pharmaceutical opioids, symptoms of opioid dependence, and a greater number of pharmaceutical opioids used in lifetime were statistically significant predictors of illicit buprenorphine use. Qualitative interviews revealed that buprenorphine was more commonly used by more experienced users who were introduced to it by their "junkie friends." Those who used buprenorphine to self-medicate withdrawal referred to it as a "miracle pill." When used to get high, reported experiences ranged from "the best high ever" to "puking for days." Participants reported using buprenorphine/naloxone orally or by intranasal inhalation. Injection of buprenorphine without naloxone was also reported.
CONCLUSION: Our findings suggest that illicit buprenorphine use is gaining ground primarily among whites and those who are more advanced in their drug use careers. Continued monitoring is needed to better understand evolving patterns and trends of illicit buprenorphine use.
Authors:
Raminta Daniulaityte; Russel Falck; Robert G Carlson
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2011-10-28
Journal Detail:
Title:  Drug and alcohol dependence     Volume:  122     ISSN:  1879-0046     ISO Abbreviation:  Drug Alcohol Depend     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-16     Completed Date:  2013-01-28     Revised Date:  2014-09-13    
Medline Journal Info:
Nlm Unique ID:  7513587     Medline TA:  Drug Alcohol Depend     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  201-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Analgesics, Opioid* / administration & dosage
Buprenorphine* / administration & dosage
Female
Humans
Male
Opioid-Related Disorders / diagnosis*,  epidemiology*
Residence Characteristics*
Self Report
Young Adult
Grant Support
ID/Acronym/Agency:
R01 DA023577/DA/NIDA NIH HHS; R01 DA023577-01A1/DA/NIDA NIH HHS; R01 DA023577-02/DA/NIDA NIH HHS; R01 DA023577-03/DA/NIDA NIH HHS; R01 DA023577-04/DA/NIDA NIH HHS; R01 DA023577-05/DA/NIDA NIH HHS; R01DA023577/DA/NIDA NIH HHS
Chemical
Reg. No./Substance:
0/Analgesics, Opioid; 40D3SCR4GZ/Buprenorphine
Comments/Corrections

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