Document Detail

Illegal use of nitrofurans in food animals: Contribution to human salmonellosis?
MedLine Citation:
PMID:  17002603     Owner:  NLM     Status:  MEDLINE    
Recent observations in Portugal of a remarkable incidence (65%) of Salmonella isolates from several sources (predominantly human and poultry) with decreased susceptibility to nitrofurantoin (MIC > or =64 mg/L), mostly comprising serogroup D isolates of Salmonella Enteritidis belonging to different phage types, suggest that illegal use of nitrofurans, especially in the poultry industry, might have contributed to the selection and prevalence of S. Enteritidis in food animals, and consequently to human salmonellosis in Portugal. Indiscriminate use of nitrofurans might also be implicated in the emergence of two multiresistant Salmonella Typhimurium clones disseminated throughout the country.
P Antunes; J Machado; L Peixe
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Publication Detail:
Type:  Editorial; Review    
Journal Detail:
Title:  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases     Volume:  12     ISSN:  1198-743X     ISO Abbreviation:  Clin. Microbiol. Infect.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-09-27     Completed Date:  2006-12-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9516420     Medline TA:  Clin Microbiol Infect     Country:  France    
Other Details:
Languages:  eng     Pagination:  1047-9     Citation Subset:  IM    
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MeSH Terms
Animal Husbandry / methods
Anti-Bacterial Agents / pharmacology
Anti-Infective Agents, Urinary / pharmacology
Drug Resistance, Multiple, Bacterial
Food Additives / administration & dosage
Microbial Sensitivity Tests
Nitrofurans / administration & dosage*
Nitrofurantoin / pharmacology
Portugal / epidemiology
Poultry / microbiology
Salmonella Infections / microbiology*,  prevention & control
Salmonella enteritidis / classification,  drug effects*,  isolation & purification
Salmonella typhimurium / drug effects,  isolation & purification
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Anti-Infective Agents, Urinary; 0/Food Additives; 0/Nitrofurans; 67-20-9/Nitrofurantoin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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