Document Detail

Ileus after administration of cold remedy in an elderly diabetic patient treated with acarbose.
MedLine Citation:
PMID:  11180704     Owner:  NLM     Status:  MEDLINE    
A 69-year-old type 2 diabetic man was admitted due to diabetic gangrane. He had a history of subtotal gastrectomy. During hospitalization, he was treated with regular insulin and 300 mg/day of acarbose. He developed a low grade fever, cough and nasal discharge, and was given a compound "cold" remedy with anticholenergic properties. The next day, he suffered from a paralytic ileus. Oral intake and acarbose were withheld and the ileus spontaneously resolved after 2 days. These finding indicate the possibility that the ileus was triggered by drugs with anticholinergic properties in this elderly diabetic patient treated with alpha-glucosidase inhibitors.
K Oba; R Kudo; M Yano; K Watanabe; Y Ajiro; K Okazaki; T Suzuki; H Nakano; S Metori
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of Nippon Medical School = Nippon Ika Daigaku zasshi     Volume:  68     ISSN:  1345-4676     ISO Abbreviation:  J Nippon Med Sch     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-05-31     Revised Date:  2012-09-25    
Medline Journal Info:
Nlm Unique ID:  100935589     Medline TA:  J Nippon Med Sch     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  61-4     Citation Subset:  IM    
The Division of Geriatric Medicine, Nippon Medical School, Tokyo, Japan.
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MeSH Terms
Acarbose / administration & dosage,  adverse effects*
Cholinergic Antagonists / administration & dosage,  adverse effects*
Common Cold / drug therapy
Diabetes Mellitus, Type 2 / complications,  drug therapy*
Drug Synergism
Enzyme Inhibitors / administration & dosage,  adverse effects*
Hypoglycemic Agents / administration & dosage,  adverse effects*
Intestinal Obstruction / chemically induced*
alpha-Glucosidases / antagonists & inhibitors*
Reg. No./Substance:
0/Cholinergic Antagonists; 0/Enzyme Inhibitors; 0/Hypoglycemic Agents; 56180-94-0/Acarbose; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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