| Ilelic Acids A and B, Two Unusual Triterpenes with a Seven-Membered Ring from Ilex latifolia. | |
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MedLine Citation:
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PMID: 22834418 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Two unusual triterpenes, ilelic acids A (1) and B (2), together with their biosynthetic related compounds ilelic acids C (3) and D (4) were isolated from the leaves of Ilex latifolia. Their structures with absolute configurations were elucidated by spectroscopic analysis and modified Mosher's method. The plausible biogenetic pathway of 1 and 2 is proposed. These triterpenes exhibited a potent inhibitory effect on MCF-7 and MDA-MB-231 cells. |
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Authors:
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Cun-Qin Wang; Lei Wang; Chun-Lin Fan; Dong-Mei Zhang; Xiao-Jun Huang; Ren-Wang Jiang; Liang-Liang Bai; Jun-Min Shi; Ying Wang; Wen-Cai Ye |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-7-26 |
Journal Detail:
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Title: Organic letters Volume: - ISSN: 1523-7052 ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-7-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Phytochemistry, China Pharmaceutical University , Nanjing 210009, People's Republic of China, and Institute of Traditional Chinese Medicine & Natural Products and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China. |
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