Document Detail

Ilelic Acids A and B, Two Unusual Triterpenes with a Seven-Membered Ring from Ilex latifolia.
MedLine Citation:
PMID:  22834418     Owner:  NLM     Status:  Publisher    
Two unusual triterpenes, ilelic acids A (1) and B (2), together with their biosynthetic related compounds ilelic acids C (3) and D (4) were isolated from the leaves of Ilex latifolia. Their structures with absolute configurations were elucidated by spectroscopic analysis and modified Mosher's method. The plausible biogenetic pathway of 1 and 2 is proposed. These triterpenes exhibited a potent inhibitory effect on MCF-7 and MDA-MB-231 cells.
Cun-Qin Wang; Lei Wang; Chun-Lin Fan; Dong-Mei Zhang; Xiao-Jun Huang; Ren-Wang Jiang; Liang-Liang Bai; Jun-Min Shi; Ying Wang; Wen-Cai Ye
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-26
Journal Detail:
Title:  Organic letters     Volume:  -     ISSN:  1523-7052     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Phytochemistry, China Pharmaceutical University , Nanjing 210009, People's Republic of China, and Institute of Traditional Chinese Medicine & Natural Products and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
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