Document Detail


IgM and IgG response to sheep red blood cells in mouse hepatitis virus-infected nude mice.
MedLine Citation:
PMID:  225644     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In nude mice which originally had no ability to respond to sheep red blood cells, an enhanced response to the same antigen with IgM-IgG switching was demonstrated during subacute infection with mouse hepatitis virus. IgM antibody-producing cells in the spleen were detected at days 2 to 6 after the antigen injection and IgG antibody-producing cells appeared at day 6 or later. The secondary IgG response, though not remarkable, was recognized after reinjection of the antigen 10 days after the first injection.
Authors:
T Tamura; K Fujiwara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Microbiology and immunology     Volume:  23     ISSN:  0385-5600     ISO Abbreviation:  Microbiol. Immunol.     Publication Date:  1979  
Date Detail:
Created Date:  1979-11-28     Completed Date:  1979-11-28     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7703966     Medline TA:  Microbiol Immunol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  177-83     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Antibody-Producing Cells
Erythrocytes / immunology*
Female
Hepatitis, Viral, Animal / immunology*
Immunoglobulin G / biosynthesis*
Immunoglobulin M / biosynthesis*
Immunologic Memory
Male
Mice
Mice, Nude
Murine hepatitis virus
Chemical
Reg. No./Substance:
0/Immunoglobulin G; 0/Immunoglobulin M

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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