Document Detail

IgM amyloidosis: clinical features in therapeutic outcomes.
MedLine Citation:
PMID:  21454218     Owner:  NLM     Status:  MEDLINE    
It is not widely recognized that patients with amyloidosis may be associated with an IgM monoclonal protein. We reviewed the characteristics of 22 IgM amyloidosis patients seen at Mayo Clinic from 1989 through 2010 and uniformly treated with stem cell transplantation. IgM patients are older, have a higher prevalence of neuropathy, a lower incidence of cardiac involvement (lower troponin T and NT-proBNP), and a much lower level of the involved immunoglobulin free light chain.
Morie A Gertz; Francis K Buadi; Suzanne R Hayman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical lymphoma, myeloma & leukemia     Volume:  11     ISSN:  2152-2669     ISO Abbreviation:  Clin Lymphoma Myeloma Leuk     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-04-01     Completed Date:  2011-08-30     Revised Date:  2011-10-03    
Medline Journal Info:
Nlm Unique ID:  101525386     Medline TA:  Clin Lymphoma Myeloma Leuk     Country:  United States    
Other Details:
Languages:  eng     Pagination:  146-8     Citation Subset:  IM    
Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA.
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MeSH Terms
Amyloidosis / drug therapy,  immunology*,  therapy*
Immunoglobulin M / immunology*
Stem Cell Transplantation
Treatment Outcome
Reg. No./Substance:
0/Immunoglobulin M

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