| IgM amyloidosis: clinical features in therapeutic outcomes. | |
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MedLine Citation:
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PMID: 21454218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It is not widely recognized that patients with amyloidosis may be associated with an IgM monoclonal protein. We reviewed the characteristics of 22 IgM amyloidosis patients seen at Mayo Clinic from 1989 through 2010 and uniformly treated with stem cell transplantation. IgM patients are older, have a higher prevalence of neuropathy, a lower incidence of cardiac involvement (lower troponin T and NT-proBNP), and a much lower level of the involved immunoglobulin free light chain. |
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Authors:
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Morie A Gertz; Francis K Buadi; Suzanne R Hayman |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinical lymphoma, myeloma & leukemia Volume: 11 ISSN: 2152-2669 ISO Abbreviation: Clin Lymphoma Myeloma Leuk Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-04-01 Completed Date: 2011-08-30 Revised Date: 2011-10-03 |
Medline Journal Info:
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Nlm Unique ID: 101525386 Medline TA: Clin Lymphoma Myeloma Leuk Country: United States |
Other Details:
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Languages: eng Pagination: 146-8 Citation Subset: IM |
Affiliation:
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Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA. gertz.morie@mayo.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amyloidosis
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drug therapy,
immunology*,
therapy* Female Humans Immunoglobulin M / immunology* Male Stem Cell Transplantation Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin M |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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