Document Detail

IgG4-related Disease: 2013 Update.
MedLine Citation:
PMID:  23392964     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Having diagnosed a patient as having IgG4-related disease, I would have a low threshold for recommending immune-suppressive treatment, and would make that recommendation for any patient with vascular involvement. My initial approach would be prednisone at 40-60 mg/day with a plan to reduce the dose every two weeks, e.g., 40, 30, 20, 15, 10, 7.5, 5, and 2.5 mg for 2 weeks each. In the event of relapse, I would double the current prednisone dose, slow the taper, and add azathioprine, anticipating using that drug for one year if the patient were to remain in remission. In the event or subsequent relapse, I would stop azathioprine and use rituximab. In a patient with large artery involvement, I would consult a vascular surgeon soon after diagnosis, anticipating a need for surgical repair.
Paul A Monach
Related Documents :
14678034 - The novel jak-3 inhibitor cp-690550 is a potent immunosuppressive agent in various muri...
16888784 - Effect of blood cyclosporine concentration on the outcome of hematopoietic stem cell tr...
16415894 - Subcutaneous alemtuzumab vs atg in adjusted conditioning for allogeneic transplantation...
20046574 - Two doses of humanized anti-cd25 antibody in renal transplantation: a preliminary compa...
8723494 - In vitro and in vivo activities of sch 56592 against blastomyces dermatitidis.
3392454 - Endotoxin shock in newborn dogs: serial hemodynamic studies.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current treatment options in cardiovascular medicine     Volume:  15     ISSN:  1092-8464     ISO Abbreviation:  Curr Treat Options Cardiovasc Med     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-27     Completed Date:  2013-03-28     Revised Date:  2014-04-02    
Medline Journal Info:
Nlm Unique ID:  9815942     Medline TA:  Curr Treat Options Cardiovasc Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  214-23     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effect of performing varicocelectomy before intracytoplasmic sperm injection on clinical outcomes in...
Next Document:  Influence of particle size on hardening and handling of a premixed calcium phosphate cement.