Document Detail


IgE-mediated adverse reactivity to a radiographic contrast medium.
MedLine Citation:
PMID:  1252036     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a patient with a previous history of a serious reaction after intravenous injection of the cholangiographic agent ioglycamic acid (Bilivistan), intravenous cholangiography appeared to be necessary. Therefore intradermal tests were performed in the patient and four controls with three radiographic contrast media closely related in chemical structure. In addition a Prausnitz-Kustner test with heated and unheated patient serum was performed. These tests demonstrated the presence in this patient of selective immediate-type reactivity to ioglycamic acid which was probably IgE mediated. Intravenous cholangiography with iodipamide seemed justified and resulted in no adverse reactions. Although this case may be exceptional, the results suggest that intradermal skin tests at proper concentrations may be useful in choosing the administration of radiographic contrast medium to patients with a history of prior adverse reactions.
Authors:
B G Wakkers-Garritsen; J Houwerziji; J P Nater; P J Wakkers
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of allergy     Volume:  36     ISSN:  0003-4738     ISO Abbreviation:  Ann Allergy     Publication Date:  1976 Feb 
Date Detail:
Created Date:  1976-04-27     Completed Date:  1976-04-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372346     Medline TA:  Ann Allergy     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  122-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cholangiography
Contrast Media / adverse effects*
Humans
Hypersensitivity, Immediate / chemically induced*,  immunology
Immunoglobulin E*
Intradermal Tests
Ioglycamic Acid / adverse effects
Male
Middle Aged
Skin Tests
Chemical
Reg. No./Substance:
0/Contrast Media; 2618-25-9/Ioglycamic Acid; 37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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