Document Detail


Idiopathic yellow nail syndrome successfully treated with OK-432.
MedLine Citation:
PMID:  17634713     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 70-year-old female presented with yellow discoloration of the nail beds of all fingers and toes, as well as bilateral pleural effusions. The patient was diagnosed as having the yellow nail syndrome based on the triad of yellow nails, lymphedema, and pleural effusions. The patient's intractable bilateral pleural effusion was treated with pleurodesis using OK-432. The treatment prevented the accumulation of pleural fluid for a long period of time. Pleural effusion associated with yellow nail syndrome is thought to be difficult to treat; however, this patient's excellent clinical course suggests that pleurodesis with OK-432 could be used to treat the disease in the future.
Authors:
Toru Yamagishi; Nobuyuki Hatanaka; Hirotaka Kamemura; Ichiro Nakazawa; Yusuke Hirano; Norio Kodaka; Atsuo Miura; Asako Kitahara; Tetsuro Sawata; Kimio Hosaka; Ken Sanno
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-07-17
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  46     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2007  
Date Detail:
Created Date:  2007-07-19     Completed Date:  2007-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1127-30     Citation Subset:  IM    
Affiliation:
Department of Respiratory Medicine, Toho University Ohashi Medical Center, Tokyo. shore@oha.toho-u.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Antineoplastic Agents / administration & dosage*
Female
Humans
Lymphedema / diagnosis,  therapy*
Nail Diseases / diagnosis,  therapy*
Picibanil / administration & dosage*
Pigmentation Disorders / diagnosis,  therapy*
Pleural Effusion / diagnosis,  therapy*
Pleurodesis
Syndrome
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 39325-01-4/Picibanil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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