Document Detail

Idiopathic ventricular fibrillation associated with J wave and early repolarization: a really benign electrocardiographic sign?
MedLine Citation:
PMID:  19450049     Owner:  NLM     Status:  In-Process    
Evaluation of: Sudden cardiac arrest associated with early repolarization. Haiissaguerre M, Derval N, Saccher F et al.: N. Engl. J. Med. 358, 2016-2023 (2008). In patients with idiopathic ventricular fibrillation, several kinds of electrocardiographic findings have been reported. Brugada electrocardiogram (ECG), a coved-type ST-segment elevation in the right precordial leads, is a well-known electrocardiographic sign, which is related to ventricular fibrillation leading to sudden cardiac death. By contrast, J wave and early repolarization are generally considered as benign manifestations on the ECG; however, they are reported as having the potential to cause cardiac arrhythmias at experimental studies. This study revealed that J wave and early repolarization were more frequent in patients with idiopathic ventricular fibrillation compared with control subjects (31 vs 5%; p < 0.0001). Moreover, a higher incidence of recurrent ventricular fibrillation was observed in patients with J wave and early repolarization on the ECG compared with those without such abnormalities (HR: 2.1; 95% CI: 1.2-3.5; p = 0.008). This study raises a question on the general concept that J wave and early repolarization are benign electrocardiographic patterns.
Takashi Noda; Wataru Shimizu
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Future cardiology     Volume:  5     ISSN:  1744-8298     ISO Abbreviation:  Future Cardiol     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101239345     Medline TA:  Future Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  227-9     Citation Subset:  -    
Division of Cardiology, Department of Internal Medicine, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan.
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Comment On:
N Engl J Med. 2008 May 8;358(19):2016-23   [PMID:  18463377 ]

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